For professionals in the chemical and pharmaceutical sectors, a deep understanding of key intermediates is foundational to successful research, development, and manufacturing. 3-(Methylsulfonyl)-1-propanol, identified by its CAS number 2058-49-3, is one such compound that warrants detailed attention. This article delves into its essential properties, safety considerations, and common synthesis pathways, providing valuable information for anyone looking to buy 3-(Methylsulfonyl)-1-propanol or understand its role in chemical processes.

Key Properties of 3-(Methylsulfonyl)-1-propanol

3-(Methylsulfonyl)-1-propanol (C4H10O3S) is recognized for its unique chemical structure and physical attributes. Its molecular weight is approximately 138.19 g/mol. Typically appearing as a colorless to pale yellow liquid, it possesses a high boiling point of around 349.4°C at standard pressure and a flash point of 165.1°C, indicating a degree of thermal stability. Its density is around 1.221 g/cm³. The compound exhibits good solubility in water, alcohols, and ethers, making it amenable to various reaction media. High purity, often specified at ≥99%, is critical for its use as an intermediate, particularly in sensitive applications like API synthesis. If you require this compound, seeking out a reliable manufacturer will ensure you receive a product meeting these precise specifications.

Safety Information and Handling Precautions

Like many chemical intermediates, 3-(Methylsulfonyl)-1-propanol requires careful handling. Safety data sheets (SDS) classify it as an irritating compound. Direct contact with skin, eyes, and mucous membranes should be avoided. When working with this chemical, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and protective clothing. Operations should be conducted in well-ventilated areas to prevent inhalation of vapors. In case of accidental exposure, immediate medical attention is recommended. Understanding these safety protocols is vital for laboratory personnel and production staff when they purchase this chemical.

Synthesis and Manufacturing Insights

The synthesis of 3-(Methylsulfonyl)-1-propanol typically involves the reaction of methyl sulfone with 1-propanol, often in the presence of a catalyst, followed by purification, usually via distillation. This process can be scaled up by chemical manufacturers to meet commercial demands. For businesses looking for a steady supply, identifying a competent supplier in China or elsewhere with proven synthesis capabilities and quality control is paramount. The ability of a manufacturer to consistently produce material with the desired purity and impurity profile is a key differentiator.

Applications and Market Significance

The primary utility of 3-(Methylsulfonyl)-1-propanol lies in its role as a pharmaceutical intermediate and a versatile reagent in organic synthesis. It serves as a crucial building block for producing APIs, agrochemicals, and various fine chemicals. Its consistent quality and availability are essential for industries that rely on predictable outcomes in their synthesis processes. Therefore, selecting a trustworthy supplier that guarantees product integrity and offers competitive pricing for CAS 2058-49-3 is a strategic imperative for any R&D or manufacturing operation.

By understanding the properties, safety measures, and synthesis of 3-(Methylsulfonyl)-1-propanol, businesses can make informed decisions when sourcing this vital chemical intermediate, ensuring efficiency and success in their respective fields.