In the intricate world of chemical synthesis, certain compounds serve as foundational elements, enabling the creation of complex molecules with profound impacts across industries. 3-Pyridineacrylic Acid (CAS 19337-97-4) is one such pivotal compound, particularly valued in pharmaceutical development and advanced organic chemistry. Understanding its characteristics and market availability is key for researchers and procurement specialists.

Chemical Profile of 3-Pyridineacrylic Acid
3-Pyridineacrylic Acid, chemically known as Pyridine-3-acrylic acid or 3-(3-pyridyl)acrylic acid, presents as a yellow crystalline powder. Its molecular formula, C8H7NO2, and molecular weight of approximately 149.15 g/mol are standard identifiers. With a reported melting point of 232-235°C (with decomposition), it is a stable solid at ambient temperatures. The high purity often available, typically 99% minimum, is critical for its intended uses.

Versatile Applications in Chemistry
The utility of 3-Pyridineacrylic Acid stems from its bifunctional nature, incorporating both a heterocyclic amine (pyridine) and an unsaturated carboxylic acid group. This structure facilitates its use in a range of applications:

  • Pharmaceutical Intermediates: It is a cornerstone in the synthesis of various drug candidates. Researchers utilize it to build complex molecular scaffolds for potential anti-inflammatory, anti-cancer, and other therapeutic agents.
  • Organic Synthesis Building Block: The compound readily participates in reactions like Michael additions and cross-coupling, making it an indispensable reagent for creating novel organic compounds.
  • Agrochemicals: Its structural motifs can be leveraged in the development of plant growth regulators or other crop protection agents.
  • Material Science: Emerging research explores its incorporation into functional polymers and coordination polymers, where its pyridine ring can act as a ligand.

Procurement Insights: Finding a Reliable Supplier
For professionals looking to purchase 3-Pyridineacrylic Acid, especially in bulk for industrial applications, the sourcing strategy is critical. Identifying reliable manufacturers and suppliers is the first step.

  • Quality Verification: Always request and review the Certificate of Analysis (CoA) to confirm the purity, CAS number, and other critical specifications match your requirements. A purity of 99% is a common benchmark for pharmaceutical-grade intermediates.
  • Supplier Location and Expertise: Many high-quality chemical manufacturers are located in China. When seeking to buy, inquire about the supplier's manufacturing capabilities, quality control procedures, and experience with international shipments.
  • Price Negotiation: For bulk purchases, obtaining quotes from several suppliers is recommended. Understanding the market price for 3-Pyridineacrylic Acid will empower you to negotiate effectively. Factors influencing price include purity, quantity, and lead time.
  • Sample Availability: Before committing to a large order, request a sample to test its suitability for your specific reaction conditions and analytical methods.

The Role of China in Chemical Supply
China's chemical industry offers a vast landscape of intermediate suppliers. Companies based there often provide competitive pricing and substantial production capacities. When sourcing 3-Pyridineacrylic Acid, partnering with manufacturers who prioritize quality assurance and have transparent operational practices is key to a successful procurement relationship.

In summary, 3-Pyridineacrylic Acid (CAS 19337-97-4) is a valuable chemical intermediate with significant potential in pharmaceutical research and development, as well as broader organic synthesis. By understanding its properties and employing a strategic procurement approach, businesses can effectively secure this essential compound from reliable sources, particularly from leading manufacturers in China.