The chemical landscape for pharmaceutical development is constantly evolving, with a persistent demand for high-performance intermediates that can unlock new therapeutic possibilities. Among these crucial compounds is 3-Trifluoromethyl-5-(methyl)pyrazole (CAS 10010-93-2), a versatile building block increasingly recognized for its utility in synthesizing advanced pharmaceutical agents. For professionals in the R&D and procurement sectors, identifying a trustworthy supplier for this compound is essential. This article highlights the importance of this intermediate and guides you on how to effectively buy it from reliable sources.

Understanding the Value of 3-Trifluoromethyl-5-(methyl)pyrazole

At its core, 3-Trifluoromethyl-5-(methyl)pyrazole is a heterocyclic organic compound characterized by the presence of both a trifluoromethyl group and a pyrazole ring. This unique structural combination imparts desirable properties for drug design:

  • Enhanced Metabolic Stability: The trifluoromethyl group is known for its resistance to metabolic degradation, which can lead to longer drug half-lives and improved bioavailability.
  • Modulated Lipophilicity: The -CF3 group can significantly influence a molecule's lipophilicity, affecting its ability to cross cell membranes and reach its target site.
  • Scaffolding Versatility: The pyrazole ring itself is a common pharmacophore found in numerous drugs, making this intermediate a valuable starting point for creating diverse chemical libraries and novel APIs.

These attributes make 3-Trifluoromethyl-5-(methyl)pyrazole an indispensable component in the synthesis of new drugs, particularly in areas like oncology, antivirals, and neurological disorders. Its role as a pharmaceutical intermediate cannot be overstated.

Securing Your Supply: The Role of a Reliable Manufacturer

When it comes to sourcing critical intermediates like 3-Trifluoromethyl-5-(methyl)pyrazole, partnering with a reputable manufacturer is crucial. A good manufacturer will:

  • Ensure Consistent Quality: Provide products with guaranteed purity (e.g., ≥99%) and consistent physical characteristics (e.g., white powder). Certificates of Analysis (CoA) should be readily available.
  • Offer Competitive Pricing: Due to scale and process optimization, manufacturers can often offer the most competitive price points, especially for bulk orders. Inquiring about bulk purchase options is advisable.
  • Maintain Robust Production: Possess the capacity and expertise to meet demand consistently, avoiding supply chain disruptions that can impact research timelines.
  • Provide Technical Support: Offer technical data and potentially application support to aid in your formulation process.

For those looking to buy 3-Trifluoromethyl-5-(methyl)pyrazole, engaging directly with leading manufacturers, particularly those based in regions with strong chemical production capabilities, is a prudent strategy. Many are equipped to handle international inquiries and provide efficient logistics.

How to Inquire for a Quote

The most effective way to obtain pricing and confirm availability is to submit a direct inquiry for a quote. Typically, this involves providing:

  • The exact product name and CAS number (3-Trifluoromethyl-5-(methyl)pyrazole, CAS 10010-93-2).
  • The required quantity (e.g., kilograms, drums).
  • Your company information (name, contact details).
  • Any specific quality or packaging requirements.

Leading suppliers will respond promptly, offering detailed quotations and information regarding lead times and shipping. By establishing a relationship with a trusted supplier, your R&D efforts can proceed with greater confidence and efficiency. Investigate the options available to secure this vital pharmaceutical intermediate for your next groundbreaking project.