In the intricate landscape of chemical synthesis and material science, fluorinated compounds occupy a position of significant importance due to the unique properties conferred by fluorine atoms. Among these, 4,4,4-Trifluorobutanol (CAS 461-18-7) stands out as a versatile fluorinated alcohol with a broad range of applications. This article delves into its synthesis, key chemical properties, and provides essential information for those looking to source this compound from reliable manufacturers.

The synthesis of 4,4,4-Trifluorobutanol typically involves reactions that introduce the trifluoromethyl group onto a four-carbon chain. Methods may include the reduction of corresponding trifluoromethyl ketones or esters, or reactions utilizing specific fluorinating agents. The resulting compound is a clear, colorless liquid, readily identified by its CAS number 461-18-7. Its molecular formula is C4H7F3O, and its molecular weight is approximately 128.09 g/mol. Key physical properties include a boiling point around 123°C and a refractive index of 1.3425, indicating its utility as a distinct chemical entity for precise synthetic transformations. For procurement, understanding the competitive price range from Chinese suppliers is important.

The chemical properties of 4,4,4-Trifluorobutanol make it a valuable intermediate. As a primary alcohol, it undergoes typical reactions such as esterification, etherification, and oxidation. The electron-withdrawing nature of the trifluoromethyl group influences its reactivity and the properties of its derivatives, making it a preferred choice in the synthesis of pharmaceuticals and agrochemicals where enhanced lipophilicity, metabolic stability, or specific electronic effects are desired. Many researchers and manufacturers look to buy this compound to introduce the trifluorobutyl moiety into their target molecules.

For companies and research institutions requiring 4,4,4-Trifluorobutanol, partnering with a trusted manufacturer and supplier is crucial for ensuring consistent quality and reliable delivery. China has emerged as a significant hub for chemical manufacturing, offering competitive sourcing options. We, as a dedicated manufacturer of fine chemicals, are committed to providing high-purity 4,4,4-Trifluorobutanol. We encourage interested parties to reach out for detailed product information, current pricing, and to discuss bulk purchase arrangements. Securing a dependable supply chain for such critical intermediates is vital for successful research and production outcomes.