4-Bromoacetanilide: A Crucial Building Block for Chemical Innovation
In the realm of chemical synthesis, certain molecules serve as indispensable linchpins, enabling the creation of novel compounds and advanced materials. 4-Bromoacetanilide (CAS 103-88-8) is one such critical building block, widely recognized for its utility across various sectors, including pharmaceuticals, agrochemicals, and specialty chemicals. For researchers and procurement professionals seeking to drive chemical innovation, understanding and sourcing this intermediate effectively is key.
4-Bromoacetanilide, also referred to as N-(4-Bromophenyl)acetamide, presents with a molecular formula of C8H8BrNO and a molecular weight of 214.06. Typically, it is supplied as a white to beige or light gray crystalline powder, ensuring ease of handling and visual quality assessment. A crucial factor for its application is its high purity, generally guaranteed at ≥98.0% assay. This level of precision is vital, as it directly influences the efficiency and selectivity of subsequent reactions, ultimately impacting the yield and quality of the final product.
The chemical structure of 4-Bromoacetanilide, featuring a bromo-substituted phenyl ring attached to an acetamide group, provides versatile reactivity. The bromine atom, in particular, can participate in a wide range of transformations, including metal-catalyzed cross-coupling reactions like Suzuki-Miyaura, Heck, and Buchwald-Hartwig couplings. These reactions are fundamental in modern organic synthesis for forging new carbon-carbon and carbon-heteroatom bonds, enabling the construction of complex molecular architectures.
In the pharmaceutical industry, 4-Bromoacetanilide serves as a foundational intermediate for synthesizing various Active Pharmaceutical Ingredients (APIs) and advanced drug candidates. Its ability to be readily functionalized makes it invaluable in medicinal chemistry for exploring structure-activity relationships and developing new therapeutic agents. For researchers in this field, sourcing high-purity material from a dependable manufacturer is a priority to ensure the integrity of their research and development efforts.
Similarly, the agrochemical sector benefits from the versatile nature of 4-Bromoacetanilide. It finds application in the synthesis of herbicides, insecticides, and fungicides, contributing to the development of more effective and targeted crop protection solutions. The demand for such intermediates highlights the importance of a stable and reliable supply chain, especially from established chemical producers.
For procurement specialists, selecting a supplier for 4-Bromoacetanilide involves careful consideration of several factors. Beyond product purity and specifications (like melting point 165-169 °C), aspects such as manufacturing capacity, quality control protocols, regulatory compliance, and responsive customer service are critical. We, as a leading manufacturer and supplier of specialty chemicals in China, are dedicated to meeting these demands. We invite you to contact us to inquire about purchasing 4-Bromoacetanilide, discuss bulk pricing, and explore how our commitment to quality can support your innovative chemical projects.
Perspectives & Insights
Chem Catalyst Pro
“Typically, it is supplied as a white to beige or light gray crystalline powder, ensuring ease of handling and visual quality assessment.”
Agile Thinker 7
“A crucial factor for its application is its high purity, generally guaranteed at ≥98.”
Logic Spark 24
“This level of precision is vital, as it directly influences the efficiency and selectivity of subsequent reactions, ultimately impacting the yield and quality of the final product.”