Understanding the fundamental chemical properties of an intermediate is paramount for its effective utilization in synthesis. 4-Bromobenzylamine (CAS 3959-07-7) is a compound that chemists frequently seek to buy due to its versatile reactivity. This article explores its key chemical characteristics and common applications, providing insights for researchers and formulators.

The physical appearance of 4-Bromobenzylamine is typically described as a clear, colorless liquid. Its melting point is noted around 25 °C, indicating it is a liquid at standard room temperatures. The boiling point is approximately 110-112 °C at 30 mm Hg, and its density is 1.473 g/mL at 25 °C. These physical properties are important for handling, storage, and reaction setup. Its refractive index is also provided as 1.5855-1.5875. The flash point is greater than 230 °F, contributing to its manageable safety profile when handled correctly.

Chemically, 4-Bromobenzylamine is an organic compound with the molecular formula C7H8BrN and a molecular weight of 186.05 g/mol. The presence of both a primary amine group (-NH2) and a bromine atom (-Br) attached to a benzene ring makes it a bifunctional molecule. The amine group can act as a nucleophile or a base, participating in reactions like acylation, alkylation, and amidation. The bromine atom, being an electron-withdrawing group and a good leaving group, facilitates nucleophilic aromatic substitution under certain conditions and is highly amenable to various metal-catalyzed cross-coupling reactions, such as Suzuki, Heck, and Sonogashira couplings.

These properties lend themselves to a wide array of synthetic applications. Researchers often purchase 4-Bromobenzylamine as a building block for creating more complex organic molecules. It is extensively used in the pharmaceutical industry as an intermediate for the synthesis of Active Pharmaceutical Ingredients (APIs). For example, it can be a precursor in the synthesis of anilines, benzylamines, and various heterocyclic compounds that form the core structure of many drugs. Companies looking for a reliable supplier of this intermediate can leverage its reactivity for drug discovery and development.

In conclusion, the combination of its physical state, chemical structure, and inherent reactivity makes 4-Bromobenzylamine (CAS 3959-07-7) a highly valuable intermediate. Its ease of functionalization allows chemists to efficiently construct diverse molecular scaffolds. For those needing this compound for their research, engaging with a trusted manufacturer ensures access to material with documented properties and consistent performance, ultimately aiding in successful synthesis outcomes.