The pharmaceutical industry relies heavily on a consistent supply of high-quality chemical intermediates to develop and manufacture life-saving drugs. Among these essential building blocks, 4-Bromofluorobenzene (CAS 460-00-4) plays a significant role, particularly in the synthesis of complex pharmaceutical compounds. This article explores the importance of 4-Bromofluorobenzene for R&D scientists and pharmaceutical manufacturers, highlighting its applications and considerations for procurement.

4-Bromofluorobenzene: A Key Pharmaceutical Building Block

4-Bromofluorobenzene, also known as 1-Bromo-4-fluorobenzene, is a halogenated aromatic compound valued for its chemical reactivity and structural features. Its primary application in the pharmaceutical realm is as an intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Notably, it is used in the production of certain atypical antipsychotic agents, demonstrating its utility in creating sophisticated drug molecules. The presence of both bromine and fluorine atoms on the benzene ring allows for diverse chemical transformations, making it a versatile tool for medicinal chemists.

Synthetic Utility in Drug Development

The versatility of 4-Bromofluorobenzene in organic synthesis is a major advantage for pharmaceutical R&D. It commonly participates in:

  • Cross-Coupling Reactions: Facilitated by catalysts, these reactions allow for the formation of new carbon-carbon bonds, which is fundamental in constructing the complex scaffolds of modern pharmaceuticals.
  • Grignard Reagent Formation: This reaction enables the introduction of the 4-fluorophenyl group into target molecules, a common motif in many drug structures.

These synthetic pathways are critical for creating novel drug candidates and optimizing existing pharmaceutical formulations. For scientists and product formulators, having access to a dependable source of 4-Bromofluorobenzene is thus essential.

Sourcing High-Quality 4-Bromofluorobenzene

When seeking to purchase 4-Bromofluorobenzene, pharmaceutical professionals should prioritize suppliers who offer:

  • Guaranteed Purity: Ensure the material meets stringent purity requirements (e.g., 99.5% min) with comprehensive Certificates of Analysis.
  • Consistent Supply: Partner with manufacturers who have robust production capacity and a reliable supply chain to avoid disruptions in research or manufacturing.
  • Competitive Pricing: Explore options from manufacturers in regions like China, known for their cost-effective chemical production.
  • Technical Expertise: Suppliers with a strong background in fine chemicals can offer valuable support and documentation.

As a dedicated manufacturer and supplier of pharmaceutical intermediates, we are committed to providing 4-Bromofluorobenzene that meets the highest quality standards. We understand the critical nature of this compound in drug development and are equipped to support your research and production needs. Contact us today to get a quote or to discuss your requirements for purchasing 4-Bromofluorobenzene.