In the highly regulated and specialized field of pharmaceutical manufacturing, the quality and reliability of chemical intermediates are of paramount importance. 4-Bromomethyl-2-cyanobiphenyl, identified by its CAS number 114772-54-2, stands out as a crucial component in the synthesis of Sartan-class drugs, a significant group of medications used to manage hypertension and heart conditions globally.

As an API intermediate, 4-Bromomethyl-2-cyanobiphenyl is valued for its precise chemical structure and high purity. Typically presented as an off-white to white crystalline powder, its assay often meets or exceeds 99.0%, ensuring optimal performance in complex synthetic pathways. The compound’s molecular formula (C14H10BrN) and weight (approx. 272.14 g/mol) are key identifiers, while its physical properties, such as a melting point of 125-128°C, dictate its handling and processing requirements in industrial settings.

The principal application of 4-Bromomethyl-2-cyanobiphenyl is its role in the synthesis of Sartan drugs, which are Angiotensin II Receptor Blockers (ARBs). Medications like Losartan and Olmesartan rely heavily on this intermediate to form their active pharmaceutical ingredients. These drugs are essential for millions of individuals worldwide, addressing critical cardiovascular health needs. The consistent demand for these life-saving treatments necessitates a stable and dependable supply of 4-Bromomethyl-2-cyanobiphenyl, positioning it as a strategic commodity in the pharmaceutical supply chain.

Beyond its direct use in manufacturing Sartan drugs, 4-Bromomethyl-2-cyanobiphenyl is also utilized in various research capacities. It serves as a valuable tool in medicinal chemistry for drug discovery, enabling scientists to explore new molecular structures and therapeutic pathways. Furthermore, its role in studies investigating potential genotoxic impurities in pharmaceuticals highlights its importance in ensuring drug safety and regulatory compliance. This versatility underscores its significance beyond its primary application.

For pharmaceutical companies seeking to source 4-Bromomethyl-2-cyanobiphenyl, partnering with manufacturers in China offers significant advantages. China's robust chemical industry, coupled with advanced synthesis technologies and stringent quality control, ensures the production of high-purity intermediates. By choosing a reliable supplier in China, companies can secure a consistent supply, competitive pricing, and the high quality necessary for their pharmaceutical manufacturing processes. This strategic sourcing is vital for maintaining production efficiency and meeting the growing global demand for effective cardiovascular medications.