In the realm of chemical synthesis, particular intermediates unlock pathways to a vast array of complex molecules. 4-Bromophenylhydrazine Hydrochloride, bearing the CAS number 622-88-8, is one such indispensable compound, serving as a crucial building block in both pharmaceutical development and general organic chemistry. For R&D scientists and procurement managers, understanding its properties and applications is key to efficient and successful synthesis. This article delves into why this intermediate is so valuable and how to source it effectively.

Chemical Profile and Properties

4-Bromophenylhydrazine Hydrochloride is an organic compound characterized by its molecular formula C6H8BrClN2. It typically presents as a white to off-white solid, signifying a stable form conducive to handling and precise dosing in chemical reactions. A high purity level, often exceeding 98.0%, is a standard offering, ensuring predictable reactivity and minimizing unwanted side reactions. Its low loss on drying (≤1.0%) further indicates its stability and quality, making it a dependable choice for synthesis.

Diverse Applications in Chemical Synthesis

The versatility of 4-Bromophenylhydrazine Hydrochloride stems from its chemical structure, allowing it to participate in various synthetic transformations:

  • Pharmaceutical Intermediates: It is notably used as a precursor in the synthesis of pharmaceuticals, particularly in the development of anti-tuberculosis drugs. Its ability to inhibit the growth of Mycobacterium tuberculosis makes it a critical component in this therapeutic area.
  • Organic Synthesis: As a phenylhydrazine derivative, it is instrumental in reactions such as the Fischer indole synthesis, a cornerstone for creating indole structures found in many biologically active compounds and materials. It also readily forms hydrazones with carbonyl compounds, which are versatile intermediates for further functionalization.
  • Heterocyclic Chemistry: Its structure facilitates the formation of various heterocyclic ring systems, which are fundamental in medicinal chemistry, agrochemicals, and material science.

Sourcing Strategies: Finding a Reliable Supplier

When you need to buy 4-Bromophenylhydrazine Hydrochloride, selecting the right supplier is crucial for ensuring quality and cost-effectiveness. Look for manufacturers and suppliers who:

  • Provide High Purity: Ensure the product meets your specific purity requirements, typically 98% or higher.
  • Offer Complete Documentation: Access to COA and SDS is essential for quality control and safe handling.
  • Maintain Supply Chain Stability: For R&D and production, consistent availability is paramount.
  • Offer Competitive Pricing: Partnering with manufacturers, especially those in China known for efficient production, can lead to significant cost savings.

As a premier manufacturer and supplier of pharmaceutical intermediates and fine chemicals, we are dedicated to providing high-quality 4-Bromophenylhydrazine Hydrochloride (CAS 622-88-8). We invite researchers and procurement managers to contact us for quotes, samples, and to discuss bulk purchase options. Secure your supply from a trusted source to drive your chemical synthesis projects forward.