4-Chloro-3-pyridinesulfonamide: Applications in Chemical Synthesis Beyond Inhibitors
While 4-Chloro-3-pyridinesulfonamide (CAS 33263-43-3) is widely recognized for its critical role in synthesizing carbonic anhydrase inhibitors, its utility extends significantly further into the diverse landscape of organic and medicinal chemistry. As a specialized manufacturer and supplier in China, we highlight the versatility of this compound as a building block for creating a broader array of complex molecules with potential applications in various scientific fields.
The inherent reactivity of the pyridine ring, coupled with the strategically placed chlorine and sulfonamide functionalities, makes 4-Chloro-3-pyridinesulfonamide a valuable starting material for numerous synthetic pathways. Beyond its well-documented use in creating enzyme inhibitors, this intermediate can be employed in the synthesis of novel agrochemicals, dyes, and advanced materials. The pyridine core is a ubiquitous motif in many biologically active compounds, and the ability to introduce specific substitutions at the 3 and 4 positions via this intermediate offers significant synthetic advantages. For researchers aiming to innovate, the opportunity to buy this versatile compound from a reliable source is key.
One significant area of application involves palladium-catalyzed cross-coupling reactions, such as Suzuki or Sonogashira couplings, at the C4 position (where the chlorine atom is located). These reactions allow for the facile introduction of aryl, heteroaryl, or alkynyl groups, leading to complex biaryl systems or functionalized pyridines that are central to many drug discovery programs. Similarly, the sulfonamide group can be modified, for instance, through alkylation or acylation, to introduce further complexity and tailor the properties of the final molecule. Access to high-purity 4-Chloro-3-pyridinesulfonamide from a trusted manufacturer ensures that these sophisticated transformations can be performed with high yields and selectivity.
The development of new materials also benefits from intermediates like 4-Chloro-3-pyridinesulfonamide. Its structure can be integrated into polymers or used to synthesize ligands for coordination chemistry, potentially leading to materials with unique electronic or optical properties. The ability to precisely engineer molecules for specific functions is a hallmark of modern chemical synthesis, and this pyridine derivative provides a robust platform for such endeavors. For those looking to purchase this compound, understanding the price for research-grade versus bulk quantities will aid in project planning.
As a leading chemical supplier in China, we are committed to supporting diverse research and development efforts by providing access to high-quality chemical intermediates. 4-Chloro-3-pyridinesulfonamide (CAS 33263-43-3) is a testament to this commitment, offering a gateway to a vast array of synthetic possibilities. We encourage scientists and procurement specialists to reach out to us to discuss how this intermediate can advance your projects, whether in pharmaceuticals, agrochemicals, or material science. Let us be your dependable partner for chemical innovation.
Perspectives & Insights
Bio Analyst 88
“4-Chloro-3-pyridinesulfonamide (CAS 33263-43-3) is a testament to this commitment, offering a gateway to a vast array of synthetic possibilities.”
Nano Seeker Pro
“We encourage scientists and procurement specialists to reach out to us to discuss how this intermediate can advance your projects, whether in pharmaceuticals, agrochemicals, or material science.”
Data Reader 7
“While 4-Chloro-3-pyridinesulfonamide (CAS 33263-43-3) is widely recognized for its critical role in synthesizing carbonic anhydrase inhibitors, its utility extends significantly further into the diverse landscape of organic and medicinal chemistry.”