The Role of 4-Chloro-L-phenylalanine in Peptide Synthesis and Modification
Peptide synthesis is a cornerstone of modern drug discovery and biochemical research, enabling the creation of complex biomolecules with diverse therapeutic and diagnostic applications. Among the array of specialized amino acids used in this field, 4-Chloro-L-phenylalanine (CAS: 14173-39-8) has emerged as a valuable component for peptide modification and the development of novel peptide-based agents. As a leading supplier of peptide synthesis reagents, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing researchers with high-quality materials like 4-Chloro-L-phenylalanine to drive innovation.
4-Chloro-L-phenylalanine, a synthetic amino acid derivative, offers unique advantages when incorporated into peptide sequences. Its structural similarity to natural phenylalanine, coupled with the presence of a chlorine atom, can impart specific chemical and biological properties to the resulting peptide. This modification can influence a peptide's stability, its interaction with target receptors, its pharmacokinetic profile, and its overall bioactivity. Researchers often utilize this non-proteinogenic amino acid to create peptide analogues for structure-activity relationship (SAR) studies, aiming to optimize drug candidates or develop highly specific biochemical probes.
The process of incorporating 4-Chloro-L-phenylalanine into a peptide chain typically involves solid-phase peptide synthesis (SPPS) or solution-phase methods, utilizing protected forms of the amino acid. Its availability as a high-purity reagent is critical for ensuring the successful synthesis of these modified peptides. For procurement managers and researchers seeking to buy 4-Chloro-L-phenylalanine for their peptide synthesis projects, partnering with a reliable manufacturer is essential. Our company, a prominent chemical supplier in China, ensures that our 4-Chloro-L-phenylalanine meets stringent quality standards, guaranteeing its suitability for even the most demanding peptide synthesis protocols.
The applications of peptides modified with 4-Chloro-L-phenylalanine extend across various therapeutic areas. For instance, researchers may explore its use in designing peptides with enhanced resistance to enzymatic degradation or improved membrane permeability. In neuroscience, the modification of peptide neurotransmitters or neuromodulators with this analogue can provide insights into receptor binding and signaling mechanisms. Furthermore, in the development of diagnostic agents or research tools, the unique properties conferred by the chloro-phenylalanine moiety can be leveraged to improve assay performance or target specificity.
As a manufacturer committed to supporting scientific advancement, we offer competitive pricing and a consistent supply of 4-Chloro-L-phenylalanine. Our goal is to facilitate your research and development efforts by providing easy access to this critical peptide synthesis building block. Whether you require small quantities for initial screening or larger amounts for scale-up, our team is equipped to meet your needs. Partner with us for your supply of 4-Chloro-L-phenylalanine and enhance your capabilities in peptide design and synthesis.
Perspectives & Insights
Core Pioneer 24
“Whether you require small quantities for initial screening or larger amounts for scale-up, our team is equipped to meet your needs.”
Silicon Explorer X
“Partner with us for your supply of 4-Chloro-L-phenylalanine and enhance your capabilities in peptide design and synthesis.”
Quantum Catalyst AI
“Peptide synthesis is a cornerstone of modern drug discovery and biochemical research, enabling the creation of complex biomolecules with diverse therapeutic and diagnostic applications.”