The landscape of scientific discovery is constantly evolving, driven by the development of new materials, pharmaceuticals, and technologies. Central to this progress is the availability of specialized chemical intermediates that serve as fundamental building blocks for innovation. One such compound that has garnered significant attention across various research fields is 4-(chloromethyl)pyridine hydrochloride (CAS 1822-51-1). Whether your work involves pharmaceutical synthesis, materials science, or general organic chemistry, understanding this versatile chemical and where to buy 4-(chloromethyl)pyridine hydrochloride is key.

Understanding the Chemical Profile and Reactivity

4-(Chloromethyl)pyridine hydrochloride is characterized by its chemical formula C6H7Cl2N and a molecular weight of approximately 164.03 g/mol. Typically supplied as a white crystalline powder with high purity (often ≥99%), it exhibits good solubility in water and polar organic solvents like DMSO and methanol. Its primary utility stems from the reactive chloromethyl group, which acts as an electrophilic site, readily undergoing nucleophilic substitution reactions. This makes it an excellent alkylating agent, capable of introducing the 4-pyridylmethyl moiety into a wide range of molecules. Researchers frequently search for “CAS 1822-51-1” to identify reliable sources for this intermediate.

Key Applications Driving Demand

The versatility of 4-(chloromethyl)pyridine hydrochloride is evident in its broad application spectrum:

  • Pharmaceutical Synthesis: It is a vital intermediate in the synthesis of numerous pharmaceuticals, including potent inhibitors of receptor tyrosine kinases such as VEGF receptors. This application is critical in the development of targeted cancer therapies.
  • Organic Synthesis: As a fundamental building block, it is used in academic and industrial laboratories for constructing complex organic molecules, exploring new reaction pathways, and synthesizing novel compounds for screening.
  • Materials Science: Researchers may utilize its pyridine ring for coordination chemistry or functionalize polymers and surfaces by reacting the chloromethyl group, leading to materials with tailored electronic or structural properties.
  • Agrochemicals and Fine Chemicals: Its reactive nature also makes it a valuable intermediate in the synthesis of certain agrochemicals and other specialized fine chemicals.

Strategic Sourcing for Research and Development

For procurement managers and research scientists needing to purchase 4-(chloromethyl)pyridine hydrochloride, identifying a trustworthy supplier is paramount. Factors to consider include product purity, consistency, lead times, and competitive pricing. Many organizations actively look for “4-(chloromethyl)pyridine hydrochloride supplier” or “4-(chloromethyl)pyridine hydrochloride for sale” to compare offerings. Engaging with a dedicated chemical manufacturer can ensure a stable and high-quality supply, crucial for the uninterrupted progress of R&D projects.

In conclusion, 4-(chloromethyl)pyridine hydrochloride is a highly valuable chemical intermediate that empowers scientific discovery across multiple disciplines. By understanding its properties and strategically sourcing it from reputable suppliers, researchers and developers can effectively advance their projects and contribute to significant scientific and technological breakthroughs.