The intricate world of organic chemistry relies on a vast array of building blocks, each possessing unique properties that enable the construction of complex molecules. Among these, 4-Cyano-3-methylbenzoic Acid (CAS: 73831-13-7) stands out as a versatile intermediate, particularly valued in the synthesis of specialized compounds for the pharmaceutical industry. Its distinct functional groups—a carboxylic acid, a cyano group, and a methyl substituent on a benzene ring—provide multiple points for chemical modification and reaction.

Chemical Properties and Reactivity

4-Cyano-3-methylbenzoic Acid typically presents as a white to off-white solid, with a melting point recorded at 216°C. This solid form indicates stability under standard storage conditions, typically in dry, room-temperature environments. The presence of the carboxylic acid group allows for esterification, amide formation, and salt formation, while the cyano group can undergo hydrolysis, reduction, or addition reactions. The methyl group can also participate in certain reactions, such as oxidation. This inherent reactivity makes it a valuable component in multi-step synthetic strategies, allowing chemists to introduce specific structural features into target molecules. Its molecular formula is C9H7NO2, with a molecular weight of 161.16 g/mol.

Applications in Pharmaceutical Research and Beyond

The primary recognized application for 4-Cyano-3-methylbenzoic Acid is in the pharmaceutical sector. It serves as a key reactant in the synthesis of 5,6-dihydrobenzo[h]quinazolin-4(3H)-ones. These compounds are significant due to their potential role in inhibiting the expression of streptokinase from Group A Streptococcus. By targeting this virulence factor, these derivatives contribute to the development of novel strategies for combating bacterial infections. Beyond this specific application, its structure suggests potential use in the synthesis of dyes, agrochemicals, or advanced materials, depending on further chemical transformations and the specific properties desired.

Sourcing High-Quality Intermediates

For researchers and industrial chemists, procuring high-purity 4-Cyano-3-methylbenzoic Acid is crucial for the success of their synthetic endeavors. China is a significant source for such chemical intermediates, with numerous manufacturers offering this product. When searching for a supplier, it’s important to verify purity levels (often 97% or higher), inquire about packaging options (from grams for R&D to bulk quantities for manufacturing), and compare pricing from different vendors. Establishing a reliable supply chain by partnering with reputable manufacturers ensures that your projects can proceed without interruption.

Partner with Us for Your Chemical Needs

As a specialized chemical supplier, we understand the importance of quality and reliability in organic chemistry building blocks. We connect you with trusted manufacturers of 4-Cyano-3-methylbenzoic Acid, ensuring you receive a high-quality product for your specific synthesis needs. Explore the potential of this intermediate and ensure your supply chain is robust by partnering with us.