4-Ethynyl-2,2'-bipyridine: A Key Intermediate for Pharmaceutical Research
The pharmaceutical industry is in a perpetual quest for novel molecules and efficient synthetic pathways to develop life-saving drugs. Within this landscape, specialized chemical intermediates play a pivotal role, acting as the fundamental building blocks for complex Active Pharmaceutical Ingredients (APIs). 4-Ethynyl-2,2'-bipyridine (CAS: 146548-24-5) is one such compound, offering a unique combination of structural features that make it highly valuable in pharmaceutical research and development. As a dedicated manufacturer and supplier of fine chemicals, we recognize the critical importance of providing high-purity intermediates to this vital sector.
The bipyridine motif present in 4-Ethynyl-2,2'-bipyridine is a common structural element in various biologically active molecules. Its ability to chelate metal ions also lends itself to applications in medicinal chemistry, particularly in the development of metallodrugs or diagnostics. The appended ethynyl group provides a convenient handle for further chemical modification through a variety of well-established reactions, such as Sonogashira couplings or click chemistry. This versatility allows medicinal chemists to efficiently introduce the bipyridine scaffold into target drug candidates, exploring structure-activity relationships and optimizing pharmacological properties. For pharmaceutical researchers looking to buy 4-Ethynyl-2,2'-bipyridine, partnering with a reliable manufacturer is essential for ensuring the consistency and purity required for preclinical and clinical development.
The synthesis of complex APIs often involves multi-step processes where the quality of each intermediate directly impacts the overall yield and purity of the final product. 4-Ethynyl-2,2'-bipyridine, when sourced from a reputable manufacturer, offers the high purity (typically 97% min) needed to avoid complications in downstream reactions. Our commitment to stringent quality control means that the material you receive is consistently reliable, allowing your R&D teams to focus on the chemistry rather than troubleshooting impurity issues. We serve as a trusted supplier in China, providing access to this valuable intermediate for research institutions and pharmaceutical companies globally. Obtaining a quote from us can highlight the cost-effectiveness of securing your critical building blocks.
As pharmaceutical research progresses, the demand for specialized heterocyclic intermediates like 4-Ethynyl-2,2'-bipyridine continues to grow. We are equipped to meet these demands, offering flexible packaging options from research-scale quantities to larger volumes for process development. Our expertise as a manufacturer ensures that we can support your project from early-stage discovery through to potential scale-up. By choosing us as your supplier for 4-Ethynyl-2,2'-bipyridine, you gain a partner dedicated to quality, reliability, and supporting the vital work of pharmaceutical innovation.
Perspectives & Insights
Logic Thinker AI
“The pharmaceutical industry is in a perpetual quest for novel molecules and efficient synthetic pathways to develop life-saving drugs.”
Molecule Spark 2025
“Within this landscape, specialized chemical intermediates play a pivotal role, acting as the fundamental building blocks for complex Active Pharmaceutical Ingredients (APIs).”
Alpha Pioneer 01
“4-Ethynyl-2,2'-bipyridine (CAS: 146548-24-5) is one such compound, offering a unique combination of structural features that make it highly valuable in pharmaceutical research and development.”