In the complex world of pharmaceutical development, the quality and availability of chemical intermediates are critical factors that can significantly impact the success of drug synthesis and manufacturing. 4-Hydroxy-2-Methylbenzoic Acid, identified by its CAS number 578-39-2, stands out as a crucial building block in various pharmaceutical pathways. This article delves into its properties, applications, and the importance of securing a reliable supply from experienced manufacturers.

Understanding 4-Hydroxy-2-Methylbenzoic Acid (CAS 578-39-2)

4-Hydroxy-2-Methylbenzoic Acid, with the molecular formula C8H8O3 and a molecular weight of 152.15 g/mol, is a derivative of benzoic acid. It is characterized by its white crystalline powder appearance and a melting point range of 177-181°C. These physical and chemical properties make it amenable to various chemical reactions, including esterification and other functional group transformations essential in organic synthesis.

Key Applications in Pharmaceutical Synthesis

The primary value of 4-Hydroxy-2-Methylbenzoic Acid in the pharmaceutical industry lies in its function as a key intermediate. Its structure allows it to be readily incorporated into larger, more complex molecules that eventually form active pharmaceutical ingredients (APIs). Researchers and development teams utilize this compound for:

  • Synthesis of APIs: It serves as a foundational component for a range of therapeutic compounds, contributing specific structural elements required for biological activity.
  • Drug Discovery: In the early stages of drug discovery, chemists use intermediates like 4-Hydroxy-2-Methylbenzoic Acid to explore novel molecular structures and test their pharmacological properties.
  • Process Optimization: Ensuring a consistent supply of high-purity intermediates is vital for optimizing manufacturing processes, reducing batch failures, and maintaining cost-effectiveness.

Sourcing Considerations for Pharmaceutical Intermediates

For any pharmaceutical company or contract research organization (CRO), the procurement of intermediates like 4-Hydroxy-2-Methylbenzoic Acid requires careful consideration. When looking to buy this product, it is essential to partner with a supplier that guarantees:

  • High Purity: Pharmaceutical synthesis demands exceptionally high purity levels (often >98%) to avoid unwanted by-products and ensure the efficacy and safety of the final drug product.
  • Batch-to-Batch Consistency: Consistent quality across different production batches is non-negotiable. This ensures reproducible results in synthesis and manufacturing.
  • Regulatory Compliance: While intermediates may not always require the same level of GMP compliance as final APIs, working with suppliers who understand and adhere to stringent quality standards is crucial.
  • Reliable Supply: A stable and uninterrupted supply chain is critical to prevent delays in drug development and manufacturing.

As a dedicated manufacturer and supplier of 4-Hydroxy-2-Methylbenzoic Acid, we understand the stringent requirements of the pharmaceutical industry. We ensure our product meets the highest purity standards and is available for consistent supply, supporting your critical research and production needs. Contact us today to discuss your requirements for CAS 578-39-2 and explore how our manufacturing expertise can benefit your projects.