The safety of ingredients used in consumer products, particularly cosmetics and food, is a paramount concern for both manufacturers and end-users. 4'-Hydroxyacetophenone (CAS 99-93-4) is a compound that has garnered attention for its functional properties. As a supplier of this chemical, we aim to provide clarity on its safety profile and common applications. This article reviews what is known about the safety of 4'-Hydroxyacetophenone, drawing on industry assessments and its established uses.

Understanding 4'-Hydroxyacetophenone's Properties

4'-Hydroxyacetophenone is recognized for its antioxidant, anti-inflammatory, and preservative-boosting capabilities, making it popular in cosmetic formulations. It also possesses mild flavor characteristics, leading to its use in food products. The scientific community has conducted various studies to assess its safety.

Safety Assessments and Regulatory Status:

  • Cosmetic Ingredient Review (CIR): The CIR Expert Panel has reviewed hydroxyacetophenone and generally considers it safe for use in cosmetics at recommended concentrations. While some studies have noted potential for skin irritation or sensitization in rare cases, especially with pure compound application in animal studies, its use in typical cosmetic formulations at low percentages is considered safe by regulatory bodies. It's often used to reduce the irritation potential of other preservatives.
  • Food Additive Status: In the flavor industry, 4'-Hydroxyacetophenone is often considered GRAS (Generally Recognized As Safe) by organizations like FEMA (Flavor and Extract Manufacturers Association) for its intended use as a flavoring agent. This designation is based on a history of safe consumption and scientific evaluation of its properties at low levels in food.
  • General Toxicity: Animal studies have indicated relatively low toxicity for hydroxyacetophenone. As with any chemical, high concentrations or misuse can lead to adverse effects, but in the contexts of its application as a cosmetic ingredient or flavor enhancer, the observed risk is considered minimal.

Considerations for Manufacturers

When sourcing 4'-Hydroxyacetophenone from a manufacturer like us, it is crucial to adhere to the recommended usage levels and guidelines provided by regulatory bodies and industry experts. Our commitment is to supply a high-purity product that facilitates safe and effective formulation. We provide the necessary documentation to support your product development and regulatory compliance efforts.

Conclusion:

Based on current scientific reviews and regulatory evaluations, 4'-Hydroxyacetophenone (CAS 99-93-4) is considered a safe ingredient when used appropriately in cosmetic and food products. Its beneficial properties, combined with a favorable safety profile at common use concentrations, make it a valuable component for manufacturers. If you are looking to buy 4'-Hydroxyacetophenone for your formulations, we are a reliable supplier ready to meet your needs with quality and assurance.