4-Hydroxyisobenzofuran-1,3-dione: A Versatile Organic Synthesis Intermediate
In the intricate world of organic synthesis, the availability of versatile and reliable intermediates is key to innovation and efficient production. 4-Hydroxyisobenzofuran-1,3-dione, identified by CAS number 37418-88-5, emerges as a significant player in this domain. This compound, often referred to as 3-Hydroxyphthalic anhydride, serves as a critical building block for chemists aiming to construct complex molecular structures. This article explores its properties, applications, and the advantages of sourcing it from a reputable chemical supplier.
Chemical Properties and Structure
4-Hydroxyisobenzofuran-1,3-dione boasts a molecular formula of C8H4O4 and a molecular weight of 164.12. It typically presents as a white to pale yellow powder, signifying its stable solid state at room temperature. Key specifications often include a purity of 98% minimum, a melting point range of 199-202 °C, and a high boiling point of approximately 365.4 °C at standard pressure. These characteristics make it suitable for a variety of chemical reactions, including those requiring elevated temperatures or specific reaction conditions.
Key Applications in Organic Synthesis
The true value of 4-Hydroxyisobenzofuran-1,3-dione lies in its broad applicability within organic chemistry:
- Building Block for Complex Molecules: Its dual functionality—the anhydride and hydroxyl groups—allows for diverse derivatization. It can readily participate in reactions to form esters, amides, and heterocyclic systems, crucial steps in synthesizing advanced organic compounds.
- Precursor in Pharmaceutical Synthesis: As an intermediate, it plays a role in the development pathways for various pharmaceutical agents. Its structure can be incorporated into drug molecules to impart specific biological activities or improve pharmacokinetic properties. We offer this as a high-quality pharmaceutical intermediate from our China manufacturing base.
- Research and Development: In academic and industrial research settings, 4-Hydroxyisobenzofuran-1,3-dione is utilized as a biochemical reagent and a foundational compound for exploring new chemical transformations and novel material development.
- Potential in Material Science: Its unique structure makes it a candidate for incorporation into polymers or functional materials, opening avenues for innovation in material science applications.
Sourcing Excellence from a Trusted Supplier
For chemists and procurement professionals seeking to buy 4-Hydroxyisobenzofuran-1,3-dione, partnering with a reliable manufacturer is essential. We, as a leading chemical supplier based in China, provide this vital intermediate with guaranteed purity and competitive pricing. Our commitment is to ensure that you have access to the high-quality materials needed to drive your organic synthesis projects forward. We encourage you to contact us for inquiries regarding bulk orders, custom synthesis needs, and to secure a dependable supply of this indispensable chemical building block.
Perspectives & Insights
Logic Thinker AI
“It can readily participate in reactions to form esters, amides, and heterocyclic systems, crucial steps in synthesizing advanced organic compounds.”
Molecule Spark 2025
“Precursor in Pharmaceutical Synthesis: As an intermediate, it plays a role in the development pathways for various pharmaceutical agents.”
Alpha Pioneer 01
“Its structure can be incorporated into drug molecules to impart specific biological activities or improve pharmacokinetic properties.”