4-Hydroxyphenylboronic Acid Pinacol Ester: A Key Intermediate for Suzuki Coupling
In the realm of sophisticated organic synthesis, the Suzuki–Miyaura (SM) coupling reaction has established itself as a premier method for forging carbon-carbon bonds. Central to its success are organoboron reagents, and 4-Hydroxyphenylboronic Acid Pinacol Ester (HPBE), bearing the CAS number 269409-70-3, is a highly sought-after intermediate. For R&D scientists and procurement specialists, understanding its chemical attributes and sourcing it from reliable manufacturers is paramount.
The Chemical Profile of HPBE
HPBE presents as a white to tan crystalline powder, distinguished by its stability and reactivity. The pinacol ester group protects the sensitive boronic acid moiety, enhancing its shelf-life and ease of handling. This robustness is particularly beneficial for laboratories and production facilities that require consistent material performance. Its widespread use in Suzuki coupling stems from its effectiveness in introducing the hydroxyphenyl group, a common structural element in many pharmaceuticals and functional materials. For those looking to buy 4-hydroxyphenylboronic acid pinacol ester, identifying a trustworthy supplier or manufacturer is the first step toward ensuring synthesis success.
Leveraging HPBE in Synthesis
The SM coupling reaction's ability to efficiently join diverse molecular fragments has made it indispensable in drug discovery, agrochemical development, and advanced materials research. HPBE is frequently selected as the organoboron component due to its reliable performance and the facile introduction of its hydroxyphenyl functionality. Procurement managers understand the importance of securing high-purity intermediates at a competitive price to optimize project budgets and timelines. Our commitment as a manufacturer is to provide exactly that: quality, consistency, and value.
Industrial Applications Driving Demand
- Pharmaceutical Intermediates: HPBE is a critical building block in the synthesis of numerous APIs and drug candidates, enabling the creation of complex organic frameworks.
- Agrochemicals: It aids in developing next-generation pesticides and herbicides, contributing to sustainable agricultural practices.
- Specialty Chemicals: HPBE is used in synthesizing advanced materials, including OLEDs and conductive polymers, pushing the boundaries of technological innovation.
Strategic Sourcing from NINGBO INNO PHARMCHEM CO.,LTD.
As a premier manufacturer and supplier based in China, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality 4-Hydroxyphenylboronic Acid Pinacol Ester. We understand the critical needs of the B2B chemical market and strive to deliver products that meet exacting standards. Our focus on quality control and efficient logistics ensures that you receive dependable materials for your synthesis projects. We offer competitive pricing and technical support, making us an ideal partner for your chemical procurement needs. Let us be your trusted source for this essential intermediate.
In summary, 4-Hydroxyphenylboronic Acid Pinacol Ester is a cornerstone reagent for modern organic synthesis. Its favorable properties and broad applicability in Suzuki coupling make it an invaluable component for researchers and manufacturers alike. Partner with us for reliable supply and exceptional quality.
Perspectives & Insights
Chem Catalyst Pro
“In the realm of sophisticated organic synthesis, the Suzuki–Miyaura (SM) coupling reaction has established itself as a premier method for forging carbon-carbon bonds.”
Agile Thinker 7
“Central to its success are organoboron reagents, and 4-Hydroxyphenylboronic Acid Pinacol Ester (HPBE), bearing the CAS number 269409-70-3, is a highly sought-after intermediate.”
Logic Spark 24
“For R&D scientists and procurement specialists, understanding its chemical attributes and sourcing it from reliable manufacturers is paramount.”