4-Methylthiazole-5-carboxaldehyde, with CAS number 82294-70-0, is a compound of significant interest to researchers and scientists across various disciplines, particularly in pharmaceutical development and advanced organic synthesis. Its unique molecular structure, featuring a thiazole ring and an aldehyde functional group, endows it with versatile reactivity, making it a sought-after intermediate for creating complex molecules.

The compound's chemical identity is characterized by its molecular formula C5H5NOS and a molecular weight of approximately 127.16 g/mol. As noted by manufacturers and suppliers, its appearance typically ranges from white to light yellow or light orange powder. While solubility in water is slight, it participates readily in many organic reactions. Key physical properties, such as a melting point of 74-78 °C and a boiling point of 118 °C/21 mmHg, are important considerations for handling and process design.

The primary application of 4-Methylthiazole-5-carboxaldehyde lies in its role as a pharmaceutical intermediate. It serves as a critical building block in the synthesis of a wide array of therapeutic agents. Its incorporation into drug molecules can impart specific pharmacological activities, contributing to the development of new treatments for various diseases. Researchers actively explore its potential in creating novel chemical entities with enhanced biological efficacy.

Beyond pharmaceuticals, this compound finds utility in the broader field of organic synthesis. Its reactive aldehyde group allows for various chemical modifications, including Schiff base formation, Wittig reactions, and reductions, enabling the construction of diverse heterocyclic systems and functionalized molecules. This makes it valuable for developing specialty chemicals, materials science applications, and even in the flavor and fragrance industries, where its unique aroma profiles can be exploited.

For R&D professionals, sourcing high-purity 4-Methylthiazole-5-carboxaldehyde from a reliable supplier is essential. Understanding its chemical properties, handling requirements (stable under recommended conditions, incompatible with oxidizing agents), and availability from manufacturers is key to successful project outcomes. Companies seeking to buy this intermediate can benefit from detailed product information and expert support, ensuring they obtain a high-quality product for their research endeavors.