In the dynamic world of chemical manufacturing and pharmaceutical development, specific intermediates serve as foundational elements for innovation. 4-Nitro-3-(trifluoromethyl)aniline (CAS: 393-11-3) stands out as one such critical building block, essential for synthesizing a range of advanced compounds. This article provides essential information for chemical buyers and researchers looking to procure this versatile intermediate.

Understanding the Compound: Properties and Significance

4-Nitro-3-(trifluoromethyl)aniline is typically available as a powder and is recognized for its purity, often at 97%. Its chemical structure, characterized by the trifluoromethyl group and nitro substituent on an aniline ring, confers specific reactivity crucial for various synthetic pathways. With a molecular formula of C7H5F3N2O2 and a molecular weight of 206.12 g/mol, this compound is important for introducing fluorinated aromatic moieties into target molecules. Its physical properties, such as a melting point of 125-129 °C and its solubility characteristics, are key considerations for its use in research and manufacturing. Notably, its role as a metabolite of the pharmaceutical Flutamide underscores its importance in the drug development pipeline.

Applications Across Industries

The primary utility of 4-Nitro-3-(trifluoromethyl)aniline lies in its application as a pharmaceutical intermediate. It is an indispensable component in the synthesis of Flutamide, a crucial antiandrogen medication. The demand for high-purity intermediates like this is constant, as it directly impacts the efficacy and safety of the final pharmaceutical product. Beyond pharmaceuticals, this compound also finds applications in general organic synthesis. Its functional groups make it an excellent starting material for creating novel materials, agrochemicals, and specialty chemicals. Researchers often seek out reliable suppliers to buy 4-Nitro-3-(trifluoromethyl)aniline for their advanced synthesis projects.

Sourcing Strategies for Chemical Buyers

For companies looking to purchase 4-Nitro-3-(trifluoromethyl)aniline, a strategic sourcing approach is crucial. This includes:

  • Quality Assurance: Always verify the purity specifications and request Certificates of Analysis from your supplier.
  • Supplier Selection: Prioritize manufacturers with a strong reputation for quality, consistency, and reliability, especially those with expertise in producing intermediates for the pharmaceutical sector.
  • Competitive Pricing: Obtain quotes from multiple suppliers, particularly manufacturers in China, to ensure competitive 4-Nitro-3-(trifluoromethyl)aniline pricing for both R&D and bulk orders.
  • Supply Chain Management: Ensure the supplier has a robust supply chain to guarantee timely delivery and consistent availability, preventing production disruptions.

NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier dedicated to providing high-quality chemical intermediates. We are well-positioned to meet the demands of researchers and industrial clients for 4-Nitro-3-(trifluoromethyl)aniline. We invite you to contact us for a quote and to discover how our reliable supply and technical support can benefit your projects.