4-Nitro-L-phenylalanine Monohydrate: A Key Chemical Intermediate Explained
In the complex world of pharmaceutical synthesis, identifying and sourcing precise chemical intermediates is a cornerstone of successful drug development. 4-Nitro-L-phenylalanine Monohydrate, identified by its CAS number 207591-86-4, stands out as a critical amino acid derivative with significant applications, particularly in the pharmaceutical sector. This article aims to provide R&D scientists and procurement managers with a detailed understanding of this compound, its chemical characteristics, and its importance in the market.
Understanding 4-Nitro-L-phenylalanine Monohydrate
Chemically known as (2S)-2-amino-3-(4-nitrophenyl)propanoic acid hydrate, this compound is a derivative of L-phenylalanine. Its molecular formula is C9H12N2O5, with a molecular weight of 228.20 g/mol. The presence of a nitro group at the para position of the phenyl ring gives it unique reactivity, making it a valuable precursor in various organic synthesis pathways. Typically, it appears as an off-white to light yellow powder, and it is stable under standard storage conditions, making it suitable for chemical manufacturers and distributors.
Synthesis and Quality Assurance from Manufacturers
The synthesis of 4-Nitro-L-phenylalanine Monohydrate often involves the nitration of L-phenylalanine. Manufacturers pay close attention to reaction conditions to ensure selective nitration at the desired position and to obtain the monohydrate form. For professionals looking to buy this compound, understanding the synthesis process and the quality control measures employed by the supplier is crucial. High purity, often specified as ≥98%, is a key requirement for pharmaceutical intermediates, ensuring that subsequent reactions proceed without unwanted side products. Companies looking for a reliable source should inquire about the manufacturer's quality assurance protocols and the availability of detailed product specifications when requesting a quote.
Applications in Pharmaceutical Development
The primary application of 4-Nitro-L-phenylalanine Monohydrate is as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). Notably, it is a key component in the production of Zolmitriptan, a widely used medication for treating migraines. Its role as a chiral building block is indispensable in constructing the complex molecular structure of Zolmitriptan. For R&D departments, having access to this compound from a reputable supplier in China allows for efficient exploration and development of new therapeutic agents. The ability to purchase this intermediate reliably supports the entire drug development pipeline, from early-stage research to commercial manufacturing.
For those seeking to buy 4-Nitro-L-phenylalanine Monohydrate, engaging with experienced manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. provides access to a high-quality chemical intermediate that supports critical pharmaceutical applications. Our commitment to providing detailed technical information and consistent product quality makes us a trusted partner for chemical procurement needs.
Perspectives & Insights
Quantum Pioneer 24
“Applications in Pharmaceutical Development The primary application of 4-Nitro-L-phenylalanine Monohydrate is as an intermediate in the synthesis of active pharmaceutical ingredients (APIs).”
Bio Explorer X
“Notably, it is a key component in the production of Zolmitriptan, a widely used medication for treating migraines.”
Nano Catalyst AI
“Its role as a chiral building block is indispensable in constructing the complex molecular structure of Zolmitriptan.”