Understanding (4R)-4-hydroxypyrrolidin-2-one: Properties & Pharmaceutical Uses
For professionals in the chemical and pharmaceutical industries, a deep understanding of key intermediates is vital for successful synthesis and product development. (4R)-4-hydroxypyrrolidin-2-one (CAS: 22677-21-0) is a compound that warrants close attention due to its specific properties and significant role in pharmaceutical manufacturing. This chiral molecule, appearing as a white to pale yellow powder, is not merely a chemical; it's a critical component for creating advanced therapeutics. If you are considering where to buy (4R)-4-hydroxypyrrolidin-2-one, understanding its characteristics will guide your sourcing decisions.
The physical and chemical properties of (4R)-4-hydroxypyrrolidin-2-one are key to its utility. With a melting point typically between 156-160°C and a density of 1.292 g/cm³, it is a stable compound under normal storage conditions. Its optical activity, specifically [α]23/D +43° in ethanol, confirms its chiral nature, which is indispensable for stereoselective synthesis. The compound is described as slightly soluble in water, a common trait for many organic intermediates. As a manufacturer, ensuring these properties are consistently met is paramount to delivering a reliable product to the market.
The primary application driving demand for this intermediate is its role in the preparation of Oxiracetam, a well-known nootropic agent. However, its value extends significantly further. Researchers leverage its chiral framework to synthesize a diverse range of single-isomer drugs. These include compounds with potential antitumor, anesthetic, antipasmodic, anti-inflammatory, and anti-HIV activities. This versatility makes (4R)-4-hydroxypyrrolidin-2-one a sought-after building block for drug discovery programs aiming for higher specificity and reduced adverse effects. Identifying a dependable supplier that provides accurate technical data is crucial for these applications.
When procuring cas 22677-21-0, prospective buyers often evaluate the price and purity. As a leading supplier in China, we focus on delivering cost-effective solutions without compromising on the high-purity standards demanded by the pharmaceutical industry. The availability of free samples allows potential clients to verify the product’s specifications before making a purchase commitment, fostering trust and ensuring the suitability for their specific synthesis requirements.
In conclusion, (4R)-4-hydroxypyrrolidin-2-one is a valuable and versatile chiral intermediate with significant implications for pharmaceutical R&D. Its well-defined properties and critical role in synthesizing important drugs like Oxiracetam make it a staple in the chemical industry. By choosing a reputable manufacturer and supplier, you can secure a reliable source for this essential compound, driving innovation in your pharmaceutical projects.
Perspectives & Insights
Chem Catalyst Pro
“In conclusion, (4R)-4-hydroxypyrrolidin-2-one is a valuable and versatile chiral intermediate with significant implications for pharmaceutical R&D.”
Agile Thinker 7
“Its well-defined properties and critical role in synthesizing important drugs like Oxiracetam make it a staple in the chemical industry.”
Logic Spark 24
“By choosing a reputable manufacturer and supplier, you can secure a reliable source for this essential compound, driving innovation in your pharmaceutical projects.”