5-Bromo-2-fluoropyridine: A Crucial Intermediate for Pharmaceutical Synthesis
In the dynamic world of pharmaceutical research and development, access to high-quality, versatile building blocks is paramount. 5-Bromo-2-fluoropyridine, with its unique chemical structure and reactivity, stands out as a critical intermediate for synthesizing a wide array of Active Pharmaceutical Ingredients (APIs). As a leading manufacturer and supplier of this essential compound from China, we are dedicated to providing researchers and pharmaceutical companies with the purity and reliability they need to accelerate their drug discovery pipelines.
The significance of 5-Bromo-2-fluoropyridine (CAS 766-11-0) lies in its dual halogen functionality – a bromine atom and a fluorine atom attached to a pyridine ring. This configuration makes it exceptionally valuable in organic synthesis. The bromine atom is highly amenable to various cross-coupling reactions, such as Suzuki, Stille, and Heck couplings, allowing for the facile formation of carbon-carbon bonds and the construction of complex molecular architectures. Concurrently, the fluorine atom at the 2-position can participate in nucleophilic aromatic substitution reactions, providing another avenue for functionalization and diversification of molecular structures.
For pharmaceutical applications, this versatility translates into its use in developing inhibitors for various therapeutic targets. For instance, it has been employed in the synthesis of inhibitors for neuropeptide Y receptor Y5, crucial in managing metabolic disorders, and inhibitors of the main protease of SARS-CoV-2, vital in the fight against COVID-19. Furthermore, its role in creating indoleamine-2,3-dioxygenase-1 (IDO1) inhibitors is significant for cancer immunotherapy. When you buy 5-bromo-2-fluoropyridine, you are acquiring a chemical that directly contributes to the development of potentially life-saving medications.
As a reputable 5-Bromo-2-fluoropyridine manufacturer in China, our focus is on ensuring consistent quality and high purity, typically exceeding 98%. This high purity is non-negotiable for pharmaceutical synthesis, where even minor impurities can affect reaction outcomes and the efficacy of the final drug product. We understand the stringent requirements of the pharmaceutical industry and strive to meet them with every batch we supply. For those looking to purchase 5-Bromo-2-fluoropyridine, engaging with a reliable supplier is key to project success.
The availability of this intermediate at a competitive price, especially when sourced in bulk, makes it an attractive option for both small-scale research and large-scale production. We encourage R&D scientists and procurement managers to reach out to us for a detailed price quote and to discuss your specific requirements. Partnering with us ensures you not only get a high-quality product but also benefit from our expertise as a dedicated supplier in the global chemical market.
Perspectives & Insights
Chem Catalyst Pro
“For instance, it has been employed in the synthesis of inhibitors for neuropeptide Y receptor Y5, crucial in managing metabolic disorders, and inhibitors of the main protease of SARS-CoV-2, vital in the fight against COVID-19.”
Agile Thinker 7
“Furthermore, its role in creating indoleamine-2,3-dioxygenase-1 (IDO1) inhibitors is significant for cancer immunotherapy.”
Logic Spark 24
“When you buy 5-bromo-2-fluoropyridine, you are acquiring a chemical that directly contributes to the development of potentially life-saving medications.”