Material science is a rapidly evolving field where the development of novel compounds with unique properties drives innovation. Chemical intermediates, such as 5-Bromo-2-hydroxypyrimidine (CAS 38353-06-9), are instrumental in this process, acting as building blocks for advanced materials. Known for its role in synthesizing specific metallacalix[4]arenes with DNA-binding capabilities, this pyrimidine derivative, typically available as a pale yellow to yellow solid with 98% HPLC purity, is of significant interest to researchers in this domain. This article explores the applications of 5-Bromo-2-hydroxypyrimidine in material science and guides researchers on sourcing this compound from reliable manufacturers and suppliers.

The Role of Pyrimidines in Material Science

Heterocyclic compounds, including pyrimidines, are frequently incorporated into the design of functional materials due to their inherent electronic properties and structural rigidity. The ability to modify pyrimidine rings through various chemical reactions makes them versatile components for creating molecules with tailored characteristics. In material science, this often translates to applications in areas such as organic electronics, supramolecular chemistry, and the development of advanced coordination complexes. The specific functionality offered by 5-Bromo-2-hydroxypyrimidine, particularly the reactive bromine atom and the nucleophilic nitrogen atoms within the pyrimidine ring, makes it a valuable starting point for creating complex architectures.

5-Bromo-2-hydroxypyrimidine in the Synthesis of Metallacalix[4]arenes

A notable application of 5-Bromo-2-hydroxypyrimidine in material science research is its use in the preparation of platinum(II)-based metallacalix[4]arenes. These macrocyclic compounds are designed to exhibit specific non-covalent interactions, such as hydrogen bonding and π-π stacking, which are crucial for their function. In this context, the pyrimidine moiety contributes to the overall structure and electronic properties of the metallacalixarene, influencing its ability to bind with biological targets like DNA. Researchers aiming to replicate or advance such syntheses require consistent access to high-purity 5-Bromo-2-hydroxypyrimidine. For those looking to buy this essential component, working with a trusted supplier that guarantees purity is key.

Sourcing Strategies and Pricing Considerations

For material scientists and research institutions, procuring specialized chemicals like 5-Bromo-2-hydroxypyrimidine requires careful consideration of quality and cost. Direct engagement with chemical manufacturers is often the most effective way to secure this compound at a competitive price. Manufacturers based in regions with strong chemical production infrastructure, such as China, can typically offer bulk discounts and reliable supply chains. When evaluating potential suppliers, it is important to request detailed product specifications, including the 98% HPLC purity, and Certificates of Analysis (CoA). Comparing quotes from multiple sources will help identify the best value for your research needs, ensuring both quality and affordability for your material science projects.

Conclusion: Enabling Innovation with Quality Chemical Intermediates

5-Bromo-2-hydroxypyrimidine stands as a testament to the critical role of specialized chemical intermediates in advancing material science. Its application in creating complex metallacalix[4]arenes highlights its potential for innovative research. By prioritizing quality, understanding synthesis, and selecting reliable manufacturers and suppliers, researchers can effectively source this vital building block. We are committed to providing high-purity 5-Bromo-2-hydroxypyrimidine to fuel your material science discoveries and contribute to the development of next-generation materials.