In the intricate world of pharmaceutical synthesis, the selection of high-quality intermediates is foundational to the success of drug discovery and development. 5-Bromo-2-methoxypyridine, a heterocyclic compound with CAS number 13472-85-0, stands out as a particularly valuable building block. As a leading supplier of pharmaceutical raw materials, we recognize the critical role this intermediate plays and aim to inform researchers and procurement specialists about its applications.

The Chemical Profile of 5-Bromo-2-methoxypyridine

Characterized by its colorless to yellow liquid appearance and a purity level of 97% minimum, 5-Bromo-2-methoxypyridine is chemically represented by the molecular formula C6H6BrNO. Its structure, featuring a pyridine ring substituted with a bromine atom and a methoxy group, offers a strategic advantage for chemists. The bromine atom can readily participate in various cross-coupling reactions, such as Suzuki, Stille, or Buchwald-Hartwig couplings, allowing for the facile introduction of diverse functional groups. The methoxy group, meanwhile, can influence the electronic properties and reactivity of the pyridine ring.

Key Applications in Pharmaceutical Development

The versatility of 5-Bromo-2-methoxypyridine makes it a sought-after intermediate in several areas of pharmaceutical research and manufacturing:

  • API Synthesis: It is frequently employed as a key starting material or intermediate in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs). Its specific structure allows for the construction of complex molecular scaffolds found in various therapeutic agents. Researchers often look to buy this compound from reliable manufacturers to ensure the integrity of their API synthesis.
  • Drug Discovery Programs: In early-stage drug discovery, medicinal chemists utilize building blocks like 5-Bromo-2-methoxypyridine to synthesize libraries of novel compounds for biological screening. Its amenability to diverse synthetic transformations accelerates the process of identifying lead compounds.
  • Heterocyclic Chemistry: As a functionalized pyridine derivative, it is central to research in heterocyclic chemistry, a field that underpins much of modern medicinal chemistry. Understanding the synthesis and reactivity of such compounds is vital.

Why Choose a Direct Manufacturer?

When sourcing critical pharmaceutical intermediates like 5-Bromo-2-methoxypyridine (CAS 13472-85-0), partnering directly with a manufacturer offers distinct advantages. It ensures you are purchasing from a source with direct control over quality, production processes, and traceability. This direct relationship can also lead to more competitive pricing and efficient supply chain management. If you are looking for a dependable supplier for this crucial chemical, considering manufacturers based in China, known for their robust chemical production capabilities, is a wise strategy.