5-Bromofuroic acid, identified by its CAS number 585-70-6, is a heterocyclic organic compound that plays a significant role as an intermediate in various chemical synthesis processes. Its structural characteristics, featuring a furan ring with a bromine substituent and a carboxylic acid functional group, render it highly reactive and adaptable for numerous applications, particularly in the pharmaceutical and fine chemical sectors. Understanding its properties and synthesis is key for any chemist or procurement specialist looking to leverage this compound.

Chemically, 5-Bromofuroic acid (molecular formula C5H3BrO3) typically presents as a white to cream or beige crystalline solid. Its melting point is approximately 188-190 °C, indicating a relatively stable solid form at room temperature. The presence of the carboxylic acid group gives it acidic properties, with a predicted pKa of around 2.84. These properties are crucial for its handling, storage, and its behavior in reaction environments. Sourcing this material with high purity, typically above 98%, is essential for reproducible results in sensitive syntheses.

The synthesis of 5-Bromofuroic acid often involves the bromination of 2-furoic acid. A common reported method involves reacting 2-furoic acid with bromine in a solvent mixture, such as glacial acetic acid and carbon tetrachloride, followed by a controlled heating period. Post-reaction workup typically includes solvent removal, washing with water, filtration, and drying to yield the desired product. While laboratory-scale synthesis is well-documented, industrial production focuses on optimizing these steps for yield, purity, and efficiency. As a manufacturer, we focus on scalable and cost-effective production methods to ensure a consistent supply.

The industrial applications of 5-Bromofuroic acid are diverse. In the pharmaceutical industry, it serves as a fundamental building block for synthesizing a wide range of APIs and drug candidates. Its structure can be modified through various chemical reactions to create complex molecules with desired therapeutic properties. Beyond pharmaceuticals, it finds utility in the agrochemical sector, contributing to the development of new crop protection agents. Researchers also utilize it in materials science and the creation of specialty chemicals, benefiting from its reactive functional groups.

For organizations looking to acquire 5-Bromofuroic acid, finding a reliable manufacturer and supplier is paramount. We offer this compound, meeting strict purity specifications and providing competitive pricing, especially for bulk purchases. If you are involved in drug discovery, agrochemical development, or advanced organic synthesis, we encourage you to buy 5-Bromofuroic acid from us. Contact us to request a quote and discuss your specific requirements for this vital chemical intermediate.