The world of chemical synthesis relies on a vast array of intermediates, each playing a specific role in building complex molecules. Among these, pyridine derivatives hold significant importance, particularly in the pharmaceutical and agrochemical sectors. 5-Ethyl-2-pyridineethanol (CAS: 5223-06-3) is a prime example of such a crucial pyridine intermediate, widely recognized for its application in synthesizing vital APIs. This article explores its chemical characteristics, its indispensable role in pharmaceutical manufacturing, and guidance for sourcing it from reliable manufacturers.

Understanding 5-Ethyl-2-pyridineethanol: A Chemical Profile
5-Ethyl-2-pyridineethanol is characterized by its molecular formula C9H13NO and a molecular weight of 151.206. Its structure features a pyridine ring with an ethyl substituent at the 5-position and a 2-hydroxyethyl group at the 2-position. These structural features are key to its reactivity and utility in synthesis. The compound is typically supplied as a White to light yellow crystal, with a high assay purity of ≥99.0%, and a low moisture content of ≤0.5%. These specifications are vital for its use in demanding chemical processes where purity directly translates to product quality and yield.

Key Applications in Pharmaceutical Synthesis
The primary and most recognized application of 5-Ethyl-2-pyridineethanol is as a key intermediate in the synthesis of Pioglitazone hydrochloride (CAS: 112529-15-4). Pioglitazone is a widely used medication to improve insulin sensitivity in patients with type 2 diabetes. The specific arrangement of functional groups in 5-Ethyl-2-pyridineethanol makes it an ideal precursor for constructing the complex thiazolidinedione ring system of Pioglitazone. For pharmaceutical companies, ensuring a consistent supply of high-purity 5-Ethyl-2-pyridineethanol is crucial for uninterrupted production and maintaining API quality.

Why Choose a Dedicated Pyridine Intermediate Supplier?
When you need to buy 5-Ethyl-2-pyridineethanol, selecting a supplier with expertise in pyridine chemistry and pharmaceutical intermediates is paramount. NINGBO INNO PHARMCHEM CO.,LTD. excels in this area, offering:

  • Specialized Manufacturing: Our facilities are equipped for the precise synthesis and purification of pyridine derivatives like 5-Ethyl-2-pyridineethanol.
  • Quality Control: We implement rigorous quality checks to ensure every batch meets the specified purity (≥99.0%) and low moisture content (≤0.5%).
  • Supply Chain Stability: As a manufacturer based in China, we provide a stable and reliable source for this critical intermediate.
  • Competitive Pricing: We offer competitive prices for bulk purchases, making high-quality intermediates accessible for your manufacturing needs.

Important Considerations for Buyers:

  • Verify Purity: Always request a Certificate of Analysis (CoA) to confirm the assay and impurity profile.
  • Check Storage Requirements: Ensure the supplier provides appropriate packaging (e.g., 25 kg drums) and storage recommendations (cool, ventilated place) to maintain product integrity.
  • Enquire about Lead Times: Confirm delivery timelines to align with your production schedules.

Secure Your Supply
For manufacturers requiring a dependable source of 5-Ethyl-2-pyridineethanol, NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner. We are committed to delivering excellence in chemical intermediates. Contact us today to obtain a quote and discuss how we can fulfill your purchasing requirements for this essential pyridine intermediate.