For professionals in the chemical manufacturing and R&D sectors, understanding the synthesis and reliable sourcing of key intermediates is crucial for project success. This article, brought to you by NINGBO INNO PHARMCHEM CO.,LTD., a prominent China-based manufacturer, delves into the world of 5-Fluoro-2-methylbenzonitrile (CAS 77532-79-7), highlighting its synthesis, properties, and its significance as an organic synthesis intermediate.

The Synthesis Landscape of 5-Fluoro-2-methylbenzonitrile

While specific proprietary synthesis routes vary among manufacturers, compounds like 5-Fluoro-2-methylbenzonitrile (CAS 77532-79-7) are typically derived through multi-step organic synthesis processes. These often involve transformations of substituted toluene or benzonitrile precursors, incorporating fluorination and cyanation steps. The key challenges in manufacturing include achieving high yields, ensuring regioselectivity during substitution, and maintaining exceptional purity levels, often exceeding 99.0%. Our company's robust R&D capabilities and extensive experience in chemical synthesis allow us to optimize these processes for efficiency and product quality.

Key Properties and Specifications

Understanding the properties of 5-Fluoro-2-methylbenzonitrile is essential for its application. This compound (Molecular Formula: C8H6FN, Molecular Weight: 135.13800) presents as an off-white crystalline solid. Its defined melting point (42-45°C) and flash point (79°C) are critical safety and handling data for industrial users. The ≥99.0% purity specification is a testament to our manufacturing precision, ensuring its suitability for demanding organic synthesis applications where even trace impurities can impact outcomes.

Role as an Organic Synthesis Intermediate

The value of 5-Fluoro-2-methylbenzonitrile lies in its role as a versatile intermediate. The nitrile group can be readily converted into carboxylic acids, amides, or amines, while the fluorinated aromatic ring offers sites for further electrophilic or nucleophilic substitution. The methyl group also provides a handle for oxidation or other modifications. This combination of reactive sites makes it an indispensable building block for synthesizing a wide range of complex molecules, including:

  • Pharmaceutical intermediates for novel drug candidates.
  • Agrochemical compounds with enhanced efficacy.
  • Specialty materials for electronics and advanced polymers.

Why Choose NINGBO INNO PHARMCHEM CO.,LTD. for Your Sourcing Needs?

As a leading manufacturer and supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. offers significant advantages for purchasing 5-Fluoro-2-methylbenzonitrile. Our established production facilities, coupled with a commitment to quality and competitive pricing, make us an ideal partner. We support both standard orders and custom synthesis projects, ensuring you get the precise quantities and specifications you require. Our experience and robust quality control systems mean you can rely on us for consistent product quality and timely delivery.

Conclusion

5-Fluoro-2-methylbenzonitrile (CAS 77532-79-7) is a fundamental intermediate for innovation in organic chemistry. By understanding its synthesis, properties, and applications, and by partnering with a reliable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD., businesses can ensure efficient and successful development of new chemical products. Contact us today to inquire about purchasing this essential intermediate and to discuss your custom manufacturing needs.