5-Hydroxyadamantan-2-one: A Key Intermediate for Drug Discovery
In the dynamic field of drug discovery, the availability of well-characterized and high-purity chemical intermediates is non-negotiable. 5-Hydroxyadamantan-2-one (CAS 20098-14-0) is one such compound, increasingly recognized for its utility as a versatile building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs). Its unique adamantane framework offers medicinal chemists an opportunity to explore enhanced molecular properties.
The structure of 5-Hydroxyadamantan-2-one, a white powder with the molecular formula C10H14O2, is characterized by a rigid, three-dimensional adamantane cage modified with a ketone and a hydroxyl group. This structural motif can significantly influence the pharmacological profile of a drug candidate, potentially improving its potency, selectivity, and pharmacokinetic properties like absorption, distribution, metabolism, and excretion (ADME). For researchers aiming to buy 5-Hydroxyadamantan-2-one, securing material with guaranteed high purity (e.g., 99%) from a dependable manufacturer is paramount to the success of their synthetic routes.
As a critical pharmaceutical intermediate, 5-Hydroxyadamantan-2-one enables the creation of compounds with increased lipophilicity and resistance to metabolic degradation, attributes often desired in drug development. Companies relying on this intermediate often look for robust supply chains, making suppliers in China a popular choice due to their production capacity and competitive price points. When considering where to purchase this compound, it is advisable to partner with a supplier that can provide comprehensive technical documentation and a consistent supply, ensuring your drug discovery pipeline remains uninterrupted.
Perspectives & Insights
Agile Reader One
“5-Hydroxyadamantan-2-one (CAS 20098-14-0) is one such compound, increasingly recognized for its utility as a versatile building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs).”
Logic Vision Labs
“Its unique adamantane framework offers medicinal chemists an opportunity to explore enhanced molecular properties.”
Molecule Origin 88
“The structure of 5-Hydroxyadamantan-2-one, a white powder with the molecular formula C10H14O2, is characterized by a rigid, three-dimensional adamantane cage modified with a ketone and a hydroxyl group.”