In the realm of synthetic chemistry, the right building blocks can dramatically accelerate discovery and development. 5-Pyrimidinylboronic Acid (CAS: 109299-78-7) is a prime example of such a crucial intermediate, offering a valuable combination of a biologically relevant pyrimidine core and a synthetically versatile boronic acid functional group. This compound is indispensable for chemists working on complex organic molecules, particularly in the pharmaceutical and advanced materials sectors. As a premier manufacturer and supplier, we are dedicated to providing high-quality 5-Pyrimidinylboronic Acid to support your innovative projects.

Understanding the Chemical Attributes

5-Pyrimidinylboronic Acid, with its chemical formula C4H5BN2O2 and molecular weight of 123.91, is characterized by its white powder appearance and a melting point between 110-114 °C. The key to its utility lies in the boronic acid moiety (-B(OH)2), which readily participates in palladium-catalyzed cross-coupling reactions, most notably the Suzuki-Miyaura coupling. This reaction is a cornerstone of modern organic synthesis, enabling the efficient formation of new carbon-carbon bonds by linking the pyrimidine unit with aryl or heteroaryl halides.

The pyrimidine scaffold itself is a fundamental structure in numerous biologically active molecules, including many pharmaceuticals. By utilizing 5-Pyrimidinylboronic Acid, researchers can precisely engineer new molecules with tailored properties. Its application is particularly significant in the pharmaceutical industry, where it serves as a vital intermediate for synthesizing potential drug candidates. This includes the development of targeted therapies, kinase inhibitors, and other complex organic compounds that require intricate structural modifications.

Applications Across Industries

The utility of 5-Pyrimidinylboronic Acid extends beyond pharmaceutical synthesis:

  • Pharmaceutical Development: Essential for creating novel drug candidates, improving efficacy, and conducting structure-activity relationship studies.
  • Organic Synthesis: A versatile building block for constructing complex organic molecules, heterocycles, and functional materials.
  • Materials Science: It can be incorporated into polymers and other advanced materials, offering potential for new functionalities in electronics and optics.
  • Agrochemical Research: The pyrimidine core is also present in many agrochemicals, suggesting further application potential in this domain.

Why Choose a Quality Manufacturer and Supplier?

For procurement managers and R&D scientists, the decision of where to buy 5-Pyrimidinylboronic Acid is critical. The purity and consistency of chemical intermediates directly impact the success of synthetic processes and the quality of the final products. Therefore, partnering with a reliable manufacturer is essential. As a leading supplier, we emphasize:

  • High Purity Standards: Our 5-Pyrimidinylboronic Acid is guaranteed to meet high purity specifications, ensuring reliable reaction outcomes.
  • Consistent Availability: We maintain stable inventory and production capacities to meet your demand for this crucial intermediate.
  • Technical Expertise: We provide comprehensive product information and support to assist your research.
  • Competitive Pricing: As a direct manufacturer, we offer competitive pricing for your bulk purchase needs.

Sourcing chemical intermediates from reputable Chinese manufacturers offers significant advantages in terms of both quality and cost-effectiveness. We are committed to being your trusted source for high-quality 5-Pyrimidinylboronic Acid, supporting your innovation from the lab bench to production scale.

Conclusion

5-Pyrimidinylboronic Acid is an invaluable tool for chemists driving innovation in synthesis. By understanding its properties, applications, and the critical importance of sourcing from quality manufacturers and suppliers, you can ensure the efficiency and success of your projects. We invite you to connect with us to procure this essential intermediate and experience the dedication to quality and service that defines our company.