For professionals in the chemical and pharmaceutical industries, understanding the detailed technical specifications and applications of key compounds is fundamental to their work. 7-Ethyl tryptophol, identified by its CAS number 41340-36-7, is one such compound that warrants a closer look due to its significant role as a pharmaceutical intermediate. This article provides a comprehensive overview of its technical data and primary uses.

7-Ethyl tryptophol, also referred to by its IUPAC name 2-(7-ethyl-1H-indol-3-yl)ethanol, is a fine chemical with a distinct molecular structure. Its chemical formula is C12H15NO, and its molecular weight is approximately 189.25 g/mol. These fundamental properties are critical for chemists and formulators when calculating stoichiometry, designing reaction conditions, and assessing material compatibility.

Key Technical Specifications:

  • CAS Number: 41340-36-7
  • Molecular Formula: C12H15NO
  • Molecular Weight: 189.25 g/mol
  • Appearance: Typically described as a White to Pale Beige Powder. Some sources may indicate a solid form at room temperature.
  • Melting Point: Reported around 44-45°C, confirming its solid state under ambient conditions.
  • Boiling Point: Approximately 310.4°C at 760 mmHg, indicating its thermal stability under standard atmospheric pressure.
  • Purity: High purity is generally required, with specifications often stating 98% or higher, as determined by Gas Chromatography (GC).
  • Solubility: Sparingly soluble in solvents like Chloroform and Methanol, which is relevant for reaction and purification procedures.
  • Storage Conditions: Recommended storage is in a cool, dry place, often specified as refrigeration (e.g., 2-8°C) to maintain stability over time.

The primary industrial application of 7-Ethyl tryptophol is its critical function as a pharmaceutical intermediate. It serves as a precursor in the synthesis of Etodolac, a widely used non-steroidal anti-inflammatory drug (NSAID). This application means that manufacturers of Etodolac are key customers for 7-Ethyl tryptophol suppliers.

Researchers in medicinal chemistry may also utilize 7-Ethyl tryptophol as a building block for synthesizing novel indole derivatives. The indole scaffold is a common feature in many biologically active compounds, making derivatives like 7-Ethyl tryptophol valuable tools for drug discovery and development efforts. When sourcing this material for R&D, procurement managers will often look for suppliers offering smaller pack sizes alongside bulk options.

For any professional requiring this compound, it is essential to source it from reputable manufacturers and suppliers who can guarantee the specified purity and consistency. Understanding these technical details allows for informed purchasing decisions and ensures the success of downstream processes, whether for large-scale pharmaceutical production or cutting-edge research.