In the vast landscape of fine chemicals, understanding the precise properties and potential applications of each compound is essential for industrial chemists and researchers. 7-Ethylindole (CAS 22867-74-9) is a notable indole derivative with a distinct set of chemical characteristics that lend themselves to important industrial uses, primarily in the pharmaceutical sector and emerging material science applications. This article explores the fundamental chemical properties of 7-Ethylindole and outlines its key industrial applications, providing valuable information for procurement and R&D professionals.

Key Chemical Properties of 7-Ethylindole

7-Ethylindole is characterized by its unique molecular structure, comprising an indole ring system with an ethyl group attached at the 7th position. Its physical state at room temperature is typically described as a clear, colorless to light brown liquid. This liquid form, unlike many other indole derivatives which are solids, offers certain advantages in handling and processing within industrial settings.

Key properties include:

  • CAS Number: 22867-74-9
  • Molecular Formula: C10H11N
  • Molecular Weight: 145.21 g/mol
  • Appearance: Clear Colorless to Light Brown Liquid
  • Melting Point: Estimated around 82.5°C, though it often exists as a liquid at standard conditions.
  • Boiling Point: Approximately 230°C. This high boiling point indicates thermal stability suitable for various reactions.
  • Solubility: It is generally soluble in common organic solvents such as methanol and dichloromethane but is insoluble in water. This solubility profile is crucial for selecting appropriate reaction media and purification methods.
  • Density: Around 1.058 g/mL at 20°C.
  • Refractive Index: Approximately n20/D 1.603.

These properties are vital for chemists and engineers when designing synthetic routes, determining storage conditions, and predicting reactivity. For instance, its solubility dictates suitable solvents for reactions and crystallization processes.

Industrial Applications of 7-Ethylindole

The primary industrial application of 7-Ethylindole lies in its utility as a fine chemical intermediate. Specifically:

  • Pharmaceutical Synthesis: It serves as a crucial building block for the synthesis of various pharmaceutical compounds, most notably as an intermediate in the production of etodolac derivatives. For pharmaceutical manufacturers, securing a consistent supply of high-purity 7-Ethylindole is essential for efficient drug production.
  • Organic Synthesis and Research: 7-Ethylindole is also employed as a reagent in broader organic synthesis research, including the preparation of benzoheterocycles through benzannulation reactions.
  • Emerging Applications: Recent research highlights its potential as a Liquid Organic Hydrogen Carrier (LOHC), demonstrating efficient hydrogen storage and release kinetics, which could be pivotal for future clean energy solutions.

Sourcing 7-Ethylindole from China

For businesses looking to purchase 7-Ethylindole, China offers a robust market with numerous manufacturers and suppliers. When procuring this chemical, it is advisable to partner with reputable companies that can provide detailed specifications, certificates of analysis, and ensure supply chain reliability. Understanding the product's chemical properties allows for informed purchasing decisions and effective integration into your specific applications.