Advanced Analytical Techniques for 2-Chloro-4-methylaniline (CAS 615-65-6) Quality Control
Ensuring the purity and precise characterization of chemical intermediates is non-negotiable, especially for applications in pharmaceuticals, dyes, and agrochemicals. For 2-Chloro-4-methylaniline (CAS 615-65-6), a critical aromatic amine intermediate, rigorous analytical quality control is paramount. As a responsible B2B manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. employs advanced analytical techniques to guarantee the integrity and specifications of our product.
The Importance of Analytical Rigor
2-Chloro-4-methylaniline, with its distinct chemical structure, requires precise analytical methods for identification, purity assessment, and the detection of trace impurities. These methods are crucial for confirming that the material meets the high standards demanded by industries where even minor deviations can have significant consequences.
Key Analytical Techniques Employed:
* Gas Chromatography-Mass Spectrometry (GC-MS): This powerful hyphenated technique is widely used for the analysis of volatile and semi-volatile organic compounds. GC-MS allows for the separation of 2-Chloro-4-methylaniline from potential isomers and impurities based on their retention times on a GC column, followed by mass spectrometric detection. The mass spectrum provides a unique fingerprint for compound identification and can reveal the presence of related substances. It is invaluable for confirming molecular weight and fragmentation patterns.
* High-Performance Liquid Chromatography (HPLC): For compounds that might be less volatile or thermally sensitive, HPLC offers an excellent separation method. Coupled with UV-Vis or Mass Spectrometry detectors (LC-MS), HPLC can accurately quantify the main product and detect impurities, especially those with different polarity characteristics.
* Nuclear Magnetic Resonance (NMR) Spectroscopy: Both ¹H NMR and ¹³C NMR spectroscopy are indispensable for structural elucidation and confirmation. NMR provides detailed information about the connectivity of atoms, the chemical environment of protons and carbons, and can confirm the presence and positions of substituents on the aromatic ring. This is critical for verifying the identity of 2-Chloro-4-methylaniline.
* Fourier-Transform Infrared (FT-IR) Spectroscopy: FT-IR is used to identify the functional groups present in the molecule, such as N-H stretching for the amino group and C-Cl stretching. Comparing the obtained spectrum with known reference spectra or theoretical predictions aids in confirming the compound's identity.
* Other Techniques: Depending on specific requirements, techniques like Karl Fischer titration for moisture content, melting point determination (for solid samples), and elemental analysis may also be employed.
Quality Assurance from NINGBO INNO PHARMCHEM CO.,LTD.
As a leading supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. integrates these sophisticated analytical methods into our quality assurance protocols. Our commitment to delivering high-purity 2-Chloro-4-methylaniline means that every batch is thoroughly tested to ensure it meets stringent specifications. When you buy from us, you are assured of receiving a product that has undergone rigorous quality checks.
We invite researchers and procurement specialists to request a quote for 2-Chloro-4-methylaniline (CAS 615-65-6). Our dedication to analytical excellence ensures that you receive a reliable intermediate for your demanding applications, whether in pharmaceutical synthesis, dye manufacturing, or agrochemical development.
Perspectives & Insights
Logic Thinker AI
“* Nuclear Magnetic Resonance (NMR) Spectroscopy: Both ¹H NMR and ¹³C NMR spectroscopy are indispensable for structural elucidation and confirmation.”
Molecule Spark 2025
“NMR provides detailed information about the connectivity of atoms, the chemical environment of protons and carbons, and can confirm the presence and positions of substituents on the aromatic ring.”
Alpha Pioneer 01
“* Fourier-Transform Infrared (FT-IR) Spectroscopy: FT-IR is used to identify the functional groups present in the molecule, such as N-H stretching for the amino group and C-Cl stretching.”