The field of advanced chemical synthesis constantly seeks novel and reliable building blocks for drug discovery and material science. Methyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate, identified by its CAS number 1421312-34-6, emerges as a significant compound in this domain. Its complex isoquinoline structure, coupled with specific functional groups, makes it an invaluable intermediate, particularly in the pharmaceutical sector for the synthesis of Roxadustat.

Unpacking the Chemical Structure and Properties

Methyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate (MF: C18H15NO4, MW: 309.32 g/mol) is characterized by its isoquinoline core substituted with hydroxyl, methyl, and phenoxy groups, alongside a methyl ester. This intricate structure provides multiple sites for chemical modification. Its appearance as a white to off-white solid, often with a purity of 98% or higher, underscores its utility in demanding synthetic applications. As a leading chemical manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. specializes in producing such high-quality intermediates.

Synthesis Methodologies and Quality Control

The synthesis of this compound typically involves multi-step organic reactions, requiring precise control over reaction conditions to ensure high yield and purity. From sourcing raw materials to final purification, every step is critical. Rigorous quality control, employing techniques like Nuclear Magnetic Resonance (NMR) spectroscopy, Mass Spectrometry (MS), and High-Performance Liquid Chromatography (HPLC), is essential to confirm the compound's identity and purity. Researchers looking to buy this intermediate can rely on NINGBO INNO PHARMCHEM CO.,LTD. for meticulously characterized products.

Applications in Pharmaceutical R&D and Beyond

The primary application of Methyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate is its role as a key intermediate in the synthesis of Roxadustat. Roxadustat is a significant therapeutic agent used to treat anemia, particularly in patients with chronic kidney disease. Beyond its pharmaceutical applications, this compound also serves as a valuable tool in academic and industrial chemical research, facilitating the exploration of new synthetic pathways and the development of novel compounds. If you are searching for a reliable supplier of chemical intermediates, consider our offerings.

Procurement and Partnership with NINGBO INNO PHARMCHEM CO.,LTD.

For procurement professionals and research scientists, sourcing this intermediate requires identifying a trusted partner. NINGBO INNO PHARMCHEM CO.,LTD. is a professional chemical synthesis provider and API intermediate manufacturer. We offer competitive prices for Methyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate and provide comprehensive documentation to support your research and development efforts. Engaging with a reputable manufacturer in China ensures quality and efficiency in your supply chain. Reach out to us to get a quote and learn how we can support your chemical synthesis needs.