In the realm of advanced organic synthesis, the availability of specialized reagents and intermediates is crucial for innovation and efficient production. 3-Bromo-5-nitrobenzotrifluoride (CAS 630125-49-4) is one such compound that offers unique chemical properties, making it a valuable asset for chemists engaged in cutting-edge research and development. As a dedicated supplier of high-quality fine chemicals, we aim to highlight the capabilities and sourcing options for this versatile molecule.

Chemical Profile of 3-Bromo-5-nitrobenzotrifluoride
This compound, chemically known as 1-bromo-3-nitro-5-(trifluoromethyl)benzene, is a fluorinated aromatic derivative. Its structure integrates a bromine atom, a nitro group, and a trifluoromethyl group, providing multiple reactive sites for further chemical modifications. Available typically as a colorless to yellowish liquid with a purity of 98% or higher, it is stable under standard conditions and soluble in common organic solvents like chloroform and methanol, though slightly soluble in water.

Catalytic Prowess in C-X Couplings
A significant application of 3-Bromo-5-nitrobenzotrifluoride lies in its role as a catalyst, specifically as a D-glucosamine-based copper catalyst for C-X couplings. These reactions are fundamental in modern organic synthesis, enabling the formation of new carbon-heteroatom bonds, which are critical for constructing complex molecular architectures. The efficiency and selectivity offered by this catalytic system make it highly attractive for academic research and industrial applications aimed at synthesizing novel materials and pharmaceutical compounds. Procurement managers seeking to enhance their catalytic toolkit can readily buy this intermediate for experimental and production purposes.

Intermediate for Pharmaceutical and Agrochemical Synthesis
While its catalytic applications are noteworthy, 3-Bromo-5-nitrobenzotrifluoride is also a key intermediate in the synthesis of various pharmaceuticals and potentially agrochemicals. Its established use in the synthesis of Nilotinib, a crucial drug for treating CML, underscores its importance in the pharmaceutical supply chain. The trifluoromethyl group, in particular, is often incorporated into drug molecules to enhance metabolic stability, lipophilicity, and binding affinity, making fluorinated intermediates like this highly sought after.

For companies involved in drug discovery and development, sourcing a reliable supplier of high-purity 3-Bromo-5-nitrobenzotrifluoride is paramount. Understanding the manufacturing process and quality control measures of potential suppliers, especially those based in China, is a critical step in the procurement process. Competitive pricing for bulk purchases further incentivizes strategic sourcing from well-equipped manufacturing partners.

Partnering with a Reliable Manufacturer
As a dedicated manufacturer and supplier of fine chemicals, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality 3-Bromo-5-nitrobenzotrifluoride to meet the diverse needs of the chemical industry. We emphasize stringent quality control and responsive customer service, ensuring that our clients receive materials that consistently meet their specifications. We encourage researchers and procurement professionals to contact us for inquiries regarding product availability, technical specifications, and customized quotes. By choosing a trusted partner, you can ensure the seamless integration of this advanced chemical intermediate into your synthesis workflows.

In summary, 3-Bromo-5-nitrobenzotrifluoride is a versatile compound essential for modern chemical synthesis, catalysis, and pharmaceutical development. Its utility in C-X coupling reactions and as a key pharmaceutical intermediate highlights its strategic value. We invite you to explore how our high-purity product can support your advanced synthesis needs.