Cross-coupling reactions have revolutionized organic synthesis, providing efficient and selective methods for forming carbon-carbon and carbon-heteroatom bonds. These reactions are indispensable in the synthesis of complex molecules, particularly in the pharmaceutical, agrochemical, and materials science industries. 2-Bromo-3-chloroaniline (CAS: 96558-73-5) serves as an excellent substrate for many of these transformations due to its strategically placed halogen atoms. As a leading chemical manufacturer and supplier in China, we empower chemists by providing high-quality intermediates ready for these advanced synthetic techniques.

Leveraging 2-Bromo-3-chloroaniline in Key Cross-Coupling Reactions

The dual halogen substituents on 2-Bromo-3-chloroaniline offer flexibility in coupling reactions. The bromine atom is typically more reactive than the chlorine atom in palladium-catalyzed cross-coupling, allowing for sequential or selective functionalization. Key reactions include:

  • Suzuki-Miyaura Coupling: The bromo or chloro group can react with organoboron compounds (e.g., boronic acids or esters) in the presence of a palladium catalyst and a base to form new C-C bonds. This is a widely used method for introducing aryl or vinyl groups.
  • Heck Reaction: Reaction with alkenes under palladium catalysis allows for the formation of substituted alkenes.
  • Buchwald-Hartwig Amination: The halogen atoms can be replaced by various amine nucleophiles using palladium catalysis, forming diarylamines or N-aryl heterocycles. This is crucial for synthesizing many biologically active compounds.
  • Sonogashira Coupling: Coupling with terminal alkynes, often catalyzed by palladium and copper, creates new C-C bonds and introduces alkyne functionalities.

Chemists often seek to buy 2-Bromo-3-chloroaniline specifically for its utility in these sophisticated coupling methodologies. Access to a reliable CAS 96558-73-5 supplier ensures that the starting material's quality does not impede the success of these sensitive reactions.

Our Commitment as a 2-Bromo-3-chloroaniline Manufacturer

As a leading 2-Bromo-3-chloroaniline manufacturer in China, we understand the critical need for high-purity intermediates to facilitate these advanced reactions. Our manufacturing processes are designed to produce 2-Bromo-3-chloroaniline with minimal impurities, ensuring optimal reactivity and selectivity in cross-coupling protocols. When you purchase CAS 96558-73-5 from us, you can trust in the quality and consistency required for modern synthetic chemistry.

Facilitating Your Research and Production

The demand for precise molecular construction makes intermediates like 2-Bromo-3-chloroaniline essential across pharmaceuticals, agrochemicals, and materials science. Partnering with a dependable CAS 96558-73-5 supplier is key to seamless project execution. We offer competitive 2-Bromo-3-chloroaniline price and are dedicated to supporting your research and production needs with exceptional products and service.

Contact Ningbo Inno Pharmchem Co., Ltd. Today

We are eager to assist you with your chemical intermediate requirements. Reach out to us to discuss bulk orders, request free samples, or inquire about the specific applications of 2-Bromo-3-chloroaniline in your synthesis projects. Let us be your trusted partner in chemical innovation.