Peptide synthesis is a cornerstone of modern drug discovery, diagnostics, and materials science. The ability to precisely construct peptide chains with specific functionalities relies heavily on the availability of high-quality amino acid derivatives. Among these, 3-Bromo-L-phenylalanine (CAS: 82311-69-1) stands out as a versatile building block that empowers researchers to create novel peptides with tailored properties. For professionals looking to buy this essential reagent, understanding its utility and sourcing it from a reliable manufacturer is key.

What is 3-Bromo-L-phenylalanine?

3-Bromo-L-phenylalanine is a naturally occurring amino acid, phenylalanine, modified by the addition of a bromine atom at the meta position of its phenyl ring. This seemingly small chemical alteration significantly impacts its reactivity and behavior within synthesis protocols. The bromine atom can serve as a handle for further chemical modifications, introduce steric bulk, or alter electronic properties, all of which are crucial for fine-tuning peptide characteristics.

Key Applications in Peptide Synthesis

  • Incorporation of Non-Canonical Amino Acids: 3-Bromo-L-phenylalanine is a non-canonical amino acid that can be seamlessly incorporated into peptide sequences using standard solid-phase peptide synthesis (SPPS) or solution-phase methods. This allows for the creation of peptides with properties not achievable with the 20 standard amino acids.
  • Enhanced Biological Activity: The bromine substituent can influence a peptide's interaction with biological targets, potentially increasing binding affinity, improving metabolic stability, or altering receptor selectivity. This makes it invaluable for developing peptide-based therapeutics.
  • Bioconjugation and Labeling: The bromine atom provides a convenient site for post-translational modifications or bioconjugation reactions. It can be used for attachment to other molecules, surfaces, or for introducing isotopic labels for advanced research studies.
  • Structure-Activity Relationship (SAR) Studies: Researchers often use halogenated amino acids like 3-Bromo-L-phenylalanine to systematically investigate how structural changes affect a peptide's biological activity. This is fundamental to optimizing lead compounds in drug discovery.

Sourcing High-Quality Reagents from a Trusted Manufacturer

The efficacy of peptide synthesis is directly linked to the quality of the starting materials. When you choose to buy 3-Bromo-L-phenylalanine, selecting a reputable manufacturer from China ensures you receive a product with guaranteed purity (often ≥98% HPLC) and consistent performance. We pride ourselves on being such a manufacturer, offering:

  • Guaranteed Purity: Our 3-Bromo-L-phenylalanine is rigorously tested to meet high purity standards, essential for preventing truncated sequences or unwanted side products in your peptide synthesis.
  • Reliable Supply Chain: As a direct producer, we maintain a robust supply chain, ensuring consistent availability and timely delivery to support your ongoing research and development projects.
  • Technical Expertise: We offer comprehensive product information and support to help you integrate 3-Bromo-L-phenylalanine effectively into your synthesis protocols.

For those seeking to advance their peptide research, obtaining high-quality 3-Bromo-L-phenylalanine from a reliable manufacturer is a critical step. We are dedicated to supporting innovation in peptide science by providing essential, high-purity chemical building blocks. Contact us today to learn more about our product offerings and to request a quote or sample.