Granulation is a common step in pharmaceutical manufacturing, aimed at improving powder flow, compressibility, and preventing segregation. Microcrystalline Cellulose (MCC) offers significant advantages when incorporated into both wet and dry granulation processes. NINGBO INNO PHARMCHEM CO.,LTD. recognizes MCC as a key facilitator of these critical manufacturing steps.

In wet granulation with MCC, the excipient's excellent water absorption capacity plays a crucial role. It ensures even distribution of the granulating fluid, promoting uniform granule formation and preventing overwetting. This leads to more consistent drying, reduced risk of granule hardening, and ultimately, a more uniform final tablet. The wicking action of MCC helps to create a robust wet mass that is easier to process.

For dry granulation techniques, such as roller compaction, MCC is equally advantageous. It contributes to the formation of strong, well-formed ribbons that are easily milled into granules. The compressibility of MCC ensures that the resulting granules possess good flow and compaction properties, which are essential for high-speed tableting. The use of MCC in dry granulation also helps to mitigate issues with moisture-sensitive APIs.

The benefits of using MCC extend to the final tablet. Whether produced through wet or dry granulation, tablets formulated with MCC often exhibit superior hardness and lower friability. This is a direct result of MCC's ability to form strong inter-particulate bonds. The consistent performance of MCC in these processes makes it a reliable choice for manufacturers aiming for reproducible results.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying high-quality MCC that consistently delivers these benefits. By incorporating MCC into your granulation strategies, you can enhance granule quality, improve manufacturing efficiency, and produce superior final dosage forms. The versatility of MCC in both wet and dry granulation solidifies its position as a fundamental excipient in modern pharmaceutical production.