In the realm of biomedical research, certain chemical compounds play pivotal roles in advancing our understanding of complex diseases. Alloxan Monohydrate (CAS 125952) stands out as a significant chemical entity, particularly for its application in inducing experimental diabetes in animal models. This article is tailored for research scientists and procurement specialists seeking to understand and source this compound.

The Role of Alloxan Monohydrate in Diabetes Research

Alloxan, chemically known as 2,4,5,6(1H,3H)-Pyrimidinetetrone, is a pyrimidine derivative that exhibits a unique biological effect. When administered to certain laboratory animals, it selectively destroys the insulin-producing beta cells in the pancreas. This selective toxicity mimics human Type 1 diabetes, making Alloxan Monohydrate an indispensable tool for researchers investigating the pathophysiology of diabetes, testing potential therapeutic agents, and studying pancreatic islet function. The compound's structural similarity to glucose facilitates its uptake by beta cells, leading to oxidative stress and cell death.

Key Properties and Specifications

Alloxan Monohydrate (CAS 125952) is typically supplied as a white or pale yellow crystalline powder. Key specifications for researchers include:

  • Purity: High purity, often 99%, is crucial for consistent and reliable experimental outcomes.
  • Form: Monohydrate is the commonly available and stable form.
  • Solubility: It is soluble in water, which is convenient for preparing solutions for experimental administration.
  • CAS Number: 125952 is the definitive identifier for Alloxan Monohydrate.

Sourcing High-Quality Alloxan Monohydrate

For research institutions and pharmaceutical companies, securing a dependable supplier of high-quality Alloxan Monohydrate is essential. When evaluating potential manufacturers and suppliers, consider the following:

  • Manufacturer Reputation: Look for companies with a strong reputation in producing fine chemicals and pharmaceutical intermediates. NINGBO INNO PHARMCHEM CO.,LTD., a leading supplier in China, offers Alloxan Monohydrate with guaranteed purity and a commitment to quality.
  • Certificate of Analysis (CoA): A comprehensive CoA detailing purity, impurity profiles, and physical properties is vital for research integrity.
  • Bulk Purchasing Options: If your research requires significant quantities, inquire about bulk pricing and packaging options.
  • Global Shipping Capabilities: Ensure the supplier can effectively ship to your location, adhering to all relevant regulations for chemical transport.

Conclusion: Partnering for Research Success

Alloxan Monohydrate (CAS 125952) remains a cornerstone chemical for diabetes research. By partnering with a reputable manufacturer and supplier, such as NINGBO INNO PHARMCHEM CO.,LTD., research scientists can ensure they have access to the high-purity compound necessary for groundbreaking discoveries. We invite researchers to contact us to inquire about Alloxan Monohydrate pricing and availability, ensuring your lab is equipped with this critical research reagent.