The synthesis of complex pharmaceutical compounds like Amisulpride relies heavily on the availability and quality of its precursor chemicals. Methyl 4-amino-5-ethylsulfonyl-2-methoxybenzoate, identified by CAS number 80036-89-1, is a critical intermediate in this process. For researchers and manufacturers in the pharmaceutical industry, a thorough understanding of this compound's properties and its role in Amisulpride synthesis is essential for successful development and production.

The Chemical Profile of Methyl 4-amino-5-ethylsulfonyl-2-methoxybenzoate

This key intermediate, with the chemical name Methyl 4-amino-5-ethylsulfonyl-2-methoxybenzoate, has the molecular formula C11H15NO5S and a molecular weight of 273.31. It is typically supplied as a white powder. Manufacturers commonly provide it with a purity assay of 99% or higher, alongside specifications for moisture content (NMT 0.5%) and impurity levels. Understanding these details is crucial for process optimization. For instance, knowledge of its density (1.289 g/cm³) and boiling point (514.5°C at 760 mmHg) can inform handling and reaction conditions.

Ensuring Quality for Pharmaceutical Applications

The pharmaceutical industry demands the highest standards for all raw materials. When seeking to purchase Methyl 4-amino-5-ethylsulfonyl-2-methoxybenzoate, manufacturers must partner with suppliers who can guarantee consistent quality and adherence to strict specifications. This includes ensuring that the product is free from detrimental impurities that could compromise the final Amisulpride API. Reputable suppliers, often manufacturers themselves, provide detailed Certificates of Analysis (COA) and Material Safety Data Sheets (MSDS) to support these claims. The ability to buy this intermediate in bulk, typically packaged in 25kg cardboard drums, from a reliable source is fundamental for large-scale production.

Strategic Sourcing and Manufacturer Benefits

Sourcing this intermediate strategically can offer significant advantages. Partnering with a direct manufacturer, particularly one based in China, can lead to more competitive pricing and a more secure supply chain. It allows for direct communication regarding specific needs, potential for custom synthesis if required, and faster resolution of any supply chain issues. When inquiring about purchasing this chemical, it's beneficial to ask about their production capacity, quality control procedures, and lead times for delivery. This proactive approach ensures a smooth production process for Amisulpride.

In conclusion, Methyl 4-amino-5-ethylsulfonyl-2-methoxybenzoate (CAS 80036-89-1) is a vital component in Amisulpride synthesis. By understanding its chemical properties and engaging with quality-focused manufacturers and suppliers, pharmaceutical companies can ensure the production of high-quality APIs and maintain a competitive edge in the market.