Analytical Chemistry Breakthroughs: Utilizing FDAA for Amino Acid Profiling
The precise characterization of biological samples often hinges on the accurate identification and quantification of their constituent amino acids. Amino acid profiling is a vital technique in fields ranging from biochemistry and clinical diagnostics to food science and pharmaceutical research. To achieve the necessary sensitivity and specificity, especially when dealing with complex mixtures or subtle chiral differences, advanced analytical tools and reagents are indispensable. (S)-2-(5-fluoro-2,4-dinitrophenyl)amino)propanamide, widely recognized as FDAA or Marfey's Reagent, has emerged as a key player in enabling breakthroughs in amino acid profiling.
FDAA's utility lies in its ability to act as a pre-column derivatization agent for HPLC analysis. By reacting with the amino groups of amino acids, it introduces a chromophore, significantly enhancing UV detection sensitivity. This is particularly beneficial when analyzing amino acids at low concentrations or in matrices where they are not the primary analytes. Moreover, FDAA's chiral nature is critical for differentiating between enantiomers of amino acids, a common challenge in biological systems and synthetic chemistry.
When researchers and procurement managers seek to buy FDAA (CAS 95713-52-3), they are often driven by the need for reliable, high-purity reagents that can deliver reproducible results. As a dedicated manufacturer and supplier in China, we pride ourselves on providing FDAA that meets these exacting standards. Our commitment is to empower analytical chemists with the tools they need to conduct sophisticated amino acid profiling, whether it’s for metabolomics studies, drug development, or quality assurance of protein-based products.
The application of FDAA in amino acid profiling goes beyond simple detection. It enables the determination of enantiomeric excess (e.e.), providing critical insights into the stereochemical composition of amino acid samples. This is crucial for understanding protein synthesis, microbial metabolism, and the development of chiral pharmaceuticals. The ability to separate and quantify both D- and L-amino acids using standard HPLC equipment, thanks to FDAA derivatization, represents a significant advancement in analytical chemistry.
For businesses and institutions looking to enhance their amino acid analysis capabilities, partnering with a trusted supplier is key. We offer competitive pricing and a stable supply of high-quality FDAA, ensuring that your analytical workflow remains efficient and accurate. We understand the commercial imperative to source essential reagents effectively. Contact us today to request a quote for our FDAA and discover how our commitment to quality and service can support your critical analytical chemistry endeavors.
Perspectives & Insights
Alpha Spark Labs
“This is particularly beneficial when analyzing amino acids at low concentrations or in matrices where they are not the primary analytes.”
Future Pioneer 88
“Moreover, FDAA's chiral nature is critical for differentiating between enantiomers of amino acids, a common challenge in biological systems and synthetic chemistry.”
Core Explorer Pro
“When researchers and procurement managers seek to buy FDAA (CAS 95713-52-3), they are often driven by the need for reliable, high-purity reagents that can deliver reproducible results.”