In the competitive landscape of chemical manufacturing, particularly for critical intermediates like 2-Fluorobenzylamine (CAS 89-99-6), rigorous quality control and accurate purity assessment are paramount. As a leading China-based manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. places immense emphasis on employing state-of-the-art analytical techniques to guarantee the high purity and consistency of our products. This ensures that our clients receive materials that meet the most demanding specifications for pharmaceutical, agrochemical, and advanced material synthesis.

Our commitment to quality begins with the raw materials and extends through every stage of the manufacturing process. For 2-Fluorobenzylamine, a clear, colorless liquid often specified with a purity of NLT 98%, a suite of analytical methods is routinely employed. These techniques not only verify the primary compound's identity and purity but also detect and quantify any potential impurities, ensuring product integrity.

Gas Chromatography (GC) and GC-Mass Spectrometry (GC-MS)

Gas Chromatography (GC) is a cornerstone technique for assessing the purity of volatile organic compounds like 2-Fluorobenzylamine. GC separates components based on their volatility and interaction with a stationary phase. The area under the peak corresponding to 2-Fluorobenzylamine in the chromatogram provides a quantitative measure of its purity. We routinely achieve purities exceeding 98% using optimized GC methods. Coupling GC with Mass Spectrometry (GC-MS) provides an additional layer of confirmation. The mass spectrum of 2-Fluorobenzylamine offers a unique fragmentation pattern, confirming its identity, while GC-MS can also help identify and characterize any trace impurities present, providing invaluable insights into the manufacturing process and product quality. This ensures that when you buy 2-Fluorobenzylamine from us, you receive a product of exceptional quality.

High-Performance Liquid Chromatography (HPLC)

While GC is excellent for volatile compounds, High-Performance Liquid Chromatography (HPLC) is employed for compounds that may be less volatile or for specific impurity profiling. HPLC offers high resolution and sensitivity, allowing for the separation and quantification of a broad range of analytes. Using appropriate stationary and mobile phases, HPLC can effectively complement GC analysis for comprehensive purity assessment of 2-Fluorobenzylamine and its related derivatives.

Nuclear Magnetic Resonance (NMR) Spectroscopy

NMR spectroscopy, including ¹H NMR, ¹³C NMR, and ¹⁹F NMR, is indispensable for structural elucidation and confirmation. The ¹H NMR spectrum of 2-Fluorobenzylamine shows characteristic signals for the benzylic protons and the aromatic protons, with chemical shifts influenced by the fluorine substituent. The ¹³C NMR provides information about the carbon backbone, and ¹⁹F NMR offers a direct and sensitive confirmation of the fluorine atom's presence and its electronic environment. NMR also plays a vital role in identifying and characterizing impurities by revealing their unique spectral fingerprints.

Titration Analysis

For assay determination, non-aqueous titration is a classical yet robust method for quantifying the total amine content in 2-Fluorobenzylamine. By titrating the basic amine with a standardized acid in a non-aqueous solvent, we can accurately determine the percentage of the active compound. This method is often included in product specifications as a primary indicator of assay purity.

High-Resolution Mass Spectrometry (HRMS)

High-Resolution Mass Spectrometry (HRMS) is utilized to confirm the exact mass and elemental composition of 2-Fluorobenzylamine, providing unequivocal evidence of its molecular formula (C₇H₈FN). This is particularly critical when analyzing complex reaction mixtures or identifying unknown impurities.

Our stringent quality control protocols, employing these advanced analytical techniques, ensure that every batch of 2-Fluorobenzylamine we supply meets the highest standards of purity and consistency. As a trusted manufacturer and supplier, we provide our clients with the confidence that they are sourcing a reliable intermediate for their critical chemical synthesis needs. When you require 2-Fluorobenzylamine, our commitment to quality assurance provides the best foundation for your research and production.