Ensuring the purity and accurate identification of chemical compounds like 3-Methylquinoline (CAS: 612-58-8) is paramount in the chemical and pharmaceutical industries. As a manufacturer and supplier, our commitment to quality necessitates rigorous analytical testing at every stage. This article outlines the key analytical techniques employed to characterize and quantify 3-Methylquinoline, ensuring it meets the high standards our clients expect.

Spectroscopic Methods: Nuclear Magnetic Resonance (NMR) spectroscopy is fundamental for structural elucidation. Both ¹H NMR and ¹³C NMR provide detailed information about the molecule's structure, confirming the presence of the quinoline ring and the methyl substituent at the 3-position. Characteristic chemical shifts and splitting patterns are compared against known data. Mass Spectrometry (MS), particularly Electron Ionization (EI-MS), is crucial for determining the molecular weight (m/z 143) and providing characteristic fragmentation patterns that serve as a fingerprint for identification. High-Resolution Mass Spectrometry (HRMS) further enhances identification by providing precise mass measurements, allowing for the determination of the exact elemental composition.

Chromatographic Techniques: To separate 3-Methylquinoline from impurities or other components in a reaction mixture, chromatographic methods are indispensable. Gas Chromatography (GC), often coupled with Mass Spectrometry (GC-MS), is effective for analyzing volatile compounds like 3-Methylquinoline. Using specific columns and temperature programs allows for precise retention time data, which, when combined with MS fragmentation patterns, confirms identity. Liquid Chromatography (LC), particularly Ultra-High-Performance Liquid Chromatography (UHPLC) coupled with Mass Spectrometry (UHPLC-MS/MS or UHPLC-HRMS), offers high sensitivity and speed, making it suitable for complex matrices or trace analysis. These techniques are vital for assay determination and impurity profiling.

For researchers and procurement managers seeking to buy 3-Methylquinoline, our rigorous analytical quality control ensures product integrity. As a reputable supplier, we provide detailed Certificates of Analysis (CoA) based on these advanced techniques, guaranteeing purity and consistency. We invite you to request a quote and discuss your specific analytical requirements, confident in our ability to deliver a product that meets your exacting standards.