In the fast-paced world of pharmaceutical research and development, the demand for high-quality, specialized chemical intermediates is constant. 4-Bromo-2-nitrobenzaldehyde, identified by CAS number 5551-12-2, is one such compound that has garnered significant attention due to its crucial role in the synthesis of advanced therapeutic agents. As a dedicated manufacturer and supplier, we are proud to provide this essential building block to the global pharmaceutical community.

The primary driver for the demand of 4-Bromo-2-nitrobenzaldehyde lies in its utility as a precursor for synthesizing complex heterocyclic structures, which are prevalent in many active pharmaceutical ingredients (APIs). One of the most cited applications is its use in the creation of inhibitors targeting Histone Deacetylase 3 (HDAC3). HDAC3 is an enzyme implicated in various cellular processes, and its inhibition is a promising strategy for treating diseases such as cancer and inflammatory disorders.

Beyond HDAC3 inhibitors, the versatile nature of 4-Bromo-2-nitrobenzaldehyde allows it to be employed in the synthesis of a broader range of drug candidates. Its reactive aldehyde and bromo functionalities, coupled with the nitro group, enable diverse synthetic transformations. For example, it has been used in the development of small-molecule inhibitors for crucial signaling pathways, such as those involving phosphoinositide-dependent kinase-1 (PDK1), which is relevant for cell proliferation diseases. The synthesis processes often involve multi-step reactions where this intermediate is a key component.

For pharmaceutical companies looking to procure 4-Bromo-2-nitrobenzaldehyde, reliability and purity are non-negotiable. Manufacturers like ourselves ensure stringent quality control to deliver products with a minimum purity of 97.0%. The compound, typically appearing as a yellow powder, possesses specific physical and chemical properties, including a defined melting point range (95.0-99.0 °C) and molecular weight (230.02 g/mol), which are vital for consistent experimental results. When you buy this chemical, you are investing in the success of your research and development pipeline.

The global supply of 4-Bromo-2-nitrobenzaldehyde is robust, with many manufacturers based in China offering competitive pricing and bulk quantities. Procuring from a trusted supplier ensures not only the quality of the intermediate but also the stability of the supply chain, which is critical for ongoing research projects and eventual large-scale production. We encourage potential buyers to request a quotation and explore sample options to verify the quality and suitability for their specific applications.

In conclusion, 4-Bromo-2-nitrobenzaldehyde (CAS 5551-12-2) is a highly valuable intermediate in pharmaceutical synthesis, particularly for the development of HDAC3 inhibitors and other critical drug candidates. Its unique chemical structure and reactivity make it indispensable for medicinal chemists. By partnering with reputable manufacturers, pharmaceutical professionals can secure a reliable source of this compound, accelerating the discovery and development of life-saving medicines.