The pharmaceutical industry continually seeks novel molecular entities for drug discovery and development. Key to this process is the availability of versatile chemical intermediates that can be readily functionalized to create complex drug candidates. 6-Bromo-3H-isobenzofuran-1-one (CAS 19477-73-7) stands out as a valuable compound in this regard, offering a unique combination of structural features beneficial for medicinal chemistry and drug synthesis.

As a pharmaceutical intermediate, 6-Bromo-3H-isobenzofuran-1-one serves as a critical building block. Its bromine substituent on the aromatic ring provides a convenient handle for various cross-coupling reactions, enabling the introduction of diverse chemical groups. These reactions are fundamental in constructing the complex carbon frameworks often found in APIs. Researchers often buy this compound to explore novel chemical space, seeking to develop compounds with enhanced efficacy and improved pharmacokinetic profiles.

The isobenzofuranone core itself is present in various biologically active molecules. By modifying this core structure, often starting with intermediates like 6-Bromo-3H-isobenzofuran-1-one, scientists can design and synthesize compounds targeting a wide range of therapeutic areas. For example, it can be used in the synthesis of enzyme inhibitors or receptor modulators. Securing a consistent supply of high-purity 6-bromo-3h-isobenzofuran-1-one from a reliable manufacturer is crucial for the scalability of these research efforts. Reputable suppliers, especially those from China, often offer competitive price points for this essential material.

The compound's role isn't limited to just adding complexity; the bromine atom can also influence the electronic properties of the final molecule, impacting receptor binding or metabolic stability. This makes it a strategic choice in lead optimization phases of drug discovery. Therefore, having a dependable supplier that ensures consistent quality and availability is paramount for research and development teams.

When selecting a source to purchase 6-Bromo-3H-isobenzofuran-1-one, it's vital to partner with a manufacturer that adheres to strict quality control protocols. This ensures that the intermediate meets the rigorous standards required for pharmaceutical research. Look for suppliers who can provide comprehensive documentation and have a strong reputation in the fine chemical market. The accessibility of this intermediate at a reasonable price from trusted chemical suppliers empowers pharmaceutical innovation.