Methyl 2-hydroxyisobutyrate (CAS 2110-78-3) stands as a crucial intermediate in the dynamic field of pharmaceutical synthesis. Its unique chemical structure and reactivity make it an indispensable building block for creating a diverse range of active pharmaceutical ingredients (APIs) and complex drug molecules. For R&D scientists and procurement professionals, understanding its role and sourcing it effectively is paramount.

The Chemical Profile of Methyl 2-hydroxyisobutyrate
This compound, a clear, colorless liquid, boasts a purity typically exceeding 99%. Its molecular formula is C5H10O3, with a molecular weight of 118.13. The presence of a hydroxyl group and an ester functionality provides versatile reaction sites, enabling its participation in numerous synthetic pathways.

Key Applications in Pharmaceutical Synthesis

  • Intermediate for API Synthesis: Methyl 2-hydroxyisobutyrate serves as a precursor or key intermediate in the synthesis of various therapeutic agents. Its structure can be modified through esterification, alkylation, and other reactions to build more complex molecular frameworks common in pharmaceuticals.
  • Chiral Synthesis: While the common form is racemic, derivatives or specific synthetic routes can leverage its structure for the introduction of chirality, a critical aspect in modern drug development.
  • Building Block for Specialty Chemicals: Beyond direct API synthesis, it functions as a foundational component in the creation of specialized chemical entities used in drug formulation, delivery systems, or as research tools in medicinal chemistry.
  • Process Development: Its predictable reactivity and availability from reliable manufacturers make it a preferred choice during the process development and scale-up phases of drug manufacturing.

Procuring Methyl 2-hydroxyisobutyrate
For companies looking to buy Methyl 2-hydroxyisobutyrate, especially for pharmaceutical applications where quality and consistency are non-negotiable, sourcing from reputable manufacturers is essential. We, as a leading chemical supplier in China, specialize in providing high-purity Methyl 2-hydroxyisobutyrate. Our product ensures:

  • Guaranteed Purity: We adhere to strict quality control measures, offering ≥99% purity to meet pharmaceutical grade requirements.
  • Reliable Supply Chain: As a direct manufacturer, we ensure consistent availability and competitive pricing for your ongoing needs.
  • Comprehensive Documentation: We provide Certificates of Analysis (CoA) with every batch, essential for pharmaceutical regulatory compliance.

By partnering with a trusted supplier for Methyl 2-hydroxyisobutyrate, pharmaceutical companies can streamline their synthesis processes and accelerate drug development. We invite you to contact us for a quote or to discuss your specific requirements for this critical pharmaceutical intermediate.