For researchers pushing the boundaries of organic chemistry and drug discovery, access to versatile and high-quality building blocks is essential. Octahydro-1H-indole-2-carboxylic acid (H-Oic-OH), with its defined stereochemistry and chemical functionality, offers significant potential in a variety of research applications. As a supplier of fine chemicals, we aim to facilitate groundbreaking research by providing reliable access to such compounds.

H-Oic-OH: A Versatile Chiral Building Block
Octahydro-1H-indole-2-carboxylic acid (CAS: 80875-98-5) is a non-proteinogenic amino acid derivative that features a saturated indole ring system. This structural characteristic, combined with its carboxylic acid and amine functionalities, makes it a valuable starting material for synthesizing a range of complex organic molecules. Its chirality is particularly important for applications in stereoselective synthesis, where precise spatial arrangement of atoms is critical for biological activity or material properties.

Key Research Areas Utilizing H-Oic-OH

  • Pharmaceutical Lead Optimization: Researchers frequently use chiral building blocks like H-Oic-OH to introduce specific structural motifs into potential drug candidates. Modifying existing leads or designing novel compounds often involves incorporating such amino acid derivatives to enhance potency, selectivity, or pharmacokinetic properties.
  • Peptide Chemistry: While not a standard proteinogenic amino acid, H-Oic-OH can be incorporated into non-natural peptides. These modified peptides can exhibit enhanced stability against enzymatic degradation or possess unique biological activities, making them subjects of intense research in areas like peptidomimetics and novel therapeutics.
  • Asymmetric Synthesis: The inherent chirality of H-Oic-OH makes it a useful starting material or chiral auxiliary in asymmetric synthesis. Chemists can leverage its structure to control the stereochemical outcome of reactions, leading to the creation of enantiomerically pure compounds.
  • Material Science: Derivatives of H-Oic-OH might find applications in material science, for instance, in the development of functional polymers or chiral liquid crystals, where precise molecular architecture dictates material properties.
  • Chemical Library Synthesis: In the pursuit of discovering new bioactive molecules, researchers often build diverse chemical libraries. H-Oic-OH can serve as a core scaffold or a component in combinatorial chemistry approaches to generate novel compound collections for high-throughput screening.

Sourcing for Research and Development
For research laboratories, obtaining H-Oic-OH in suitable quantities and with guaranteed purity is essential. We provide this compound from our manufacturing facilities, ensuring that scientists have access to a reliable source for their R&D projects. Whether you need small quantities for exploratory studies or larger amounts for scale-up research, our commitment to quality and accessibility supports your scientific endeavors. When you need to buy H-Oic-OH for your research, consider us a dependable supplier.

The continuous exploration of novel chemical structures drives innovation in science. By providing essential building blocks like Octahydro-1H-indole-2-carboxylic acid, we aim to empower researchers in their pursuit of new discoveries and advanced chemical applications.