4-Fluorobenzenesulfonyl Chloride (CAS 349-88-2) is a chemical compound that plays a pivotal role in numerous advanced chemical synthesis processes. As a reactive sulfonylating agent, its ability to efficiently introduce sulfonyl groups makes it a sought-after intermediate for researchers and industrial chemists alike. Understanding its applications is key to leveraging its full potential in product development.

What is 4-Fluorobenzenesulfonyl Chloride?

At its core, 4-Fluorobenzenesulfonyl Chloride is a derivative of benzenesulfonyl chloride where a fluorine atom is substituted at the para (4-) position of the benzene ring. This specific structure imparts unique reactivity and selectivity, making it valuable in various chemical transformations. It typically appears as a white to light yellow crystalline solid and requires careful handling due to its sensitivity to moisture and corrosive nature.

Major Application Areas:

  1. Agrochemical Synthesis: One of the most significant applications of 4-Fluorobenzenesulfonyl Chloride is its role as a key intermediate in the synthesis of pesticides, particularly herbicides and fungicides. The sulfonyl group it introduces can be crucial for the biological activity of these compounds, contributing to effective crop protection. Procurement managers seeking reliable suppliers for agrochemical intermediates often look for this compound.
  2. Specialty Chemical Manufacturing: Beyond agrochemicals, this compound serves as a versatile building block in the broader specialty chemicals sector. It is utilized in the creation of various functional materials, dyes, and performance additives where the sulfonyl moiety is integral to the desired properties. For those looking to buy specialty chemicals, this intermediate is a valuable starting point.
  3. Organic Synthesis and Research: In academic and industrial research laboratories, 4-Fluorobenzenesulfonyl Chloride is a frequently used reagent for introducing sulfonyl groups into organic molecules. This includes the synthesis of sulfonamides and sulfonate esters, which are common motifs in medicinal chemistry and materials science. Researchers often seek out suppliers offering research-grade quantities.
  4. Peptide Modification and Polymer Chemistry: Its reactivity also extends to modifying peptides, a process important in biochemical research and the development of peptide-based therapeutics. In polymer chemistry, it can be employed to functionalize polymer chains, altering their properties for specific applications.

Why Choose a Reliable Supplier?

When procuring 4-Fluorobenzenesulfonyl Chloride, it is essential to partner with a manufacturer that guarantees purity and consistency. As a leading supplier, we provide this vital intermediate with high purity levels (≥97% GC) and reliable supply chain management, ensuring your research or production processes are not hindered. Whether you are purchasing for bulk manufacturing or R&D purposes, understanding these applications helps in identifying the right chemical solutions. We are dedicated to supporting your chemical needs from development to scale-up, offering competitive prices for this critical intermediate.