Atorvastatin Calcium Manufacturing: Sourcing Key Thiazolium Bromide
The production of atorvastatin calcium, a vital medication for managing cholesterol levels and preventing cardiovascular diseases, relies heavily on the availability of specific, high-quality chemical intermediates. Among these, 3-Ethyl-5-(2-Hydroxyethyl)-4-Methylthiazolium Bromide (CAS 54016-70-5) stands out as the primary raw material. For procurement managers and research scientists involved in API manufacturing, understanding how to effectively source this compound is key to ensuring efficient and cost-effective production.
When you need to buy 3-Ethyl-5-(2-Hydroxyethyl)-4-Methylthiazolium Bromide, the first step is to identify suppliers who can guarantee its crucial quality attributes. The article points to a high purity level of ≥99.0%, which is essential for the successful synthesis of atorvastatin calcium. Lower purity can lead to complex purification steps, reduced yields, and potential deviations in the final drug’s safety and efficacy profile. Therefore, seeking out manufacturers known for stringent quality control from regions like China is often a strategic move.
The physical form, an off-white or white crystalline powder, is indicative of its processing and suitability for pharmaceutical synthesis. However, its specific storage requirements (0-5°C and protection from moisture) mean that supply chain management is just as critical as the product itself. A reliable chemical supplier will ensure these conditions are met from their facility to yours.
For pharmaceutical companies, the decision to buy from a particular supplier involves more than just price. It’s about building a dependable supply chain. This involves looking at a supplier’s capacity, their adherence to international quality standards, and their responsiveness to inquiries regarding technical specifications and pricing. Obtaining a quote from multiple reputable manufacturers allows for a comprehensive comparison, ensuring you secure a partner that offers both competitive pricing and the unwavering quality required for atorvastatin calcium production. This focus on the core intermediate's quality is foundational to producing a safe and effective medication.
Perspectives & Insights
Future Origin 2025
“The physical form, an off-white or white crystalline powder, is indicative of its processing and suitability for pharmaceutical synthesis.”
Core Analyst 01
“However, its specific storage requirements (0-5°C and protection from moisture) mean that supply chain management is just as critical as the product itself.”
Silicon Seeker One
“A reliable chemical supplier will ensure these conditions are met from their facility to yours.”