In the pharmaceutical sector, the accurate identification and quantification of impurities are cornerstones of robust quality assurance. Azacitidine Impurity 1, officially cataloged under CAS number 157771-77-2, plays a crucial role in this analytical landscape. It is a vital reference standard, indispensable for researchers and quality control professionals working with the API Azacitidine. Understanding the significance of this impurity and its associated CAS number is key for anyone involved in pharmaceutical analysis and procurement.

The chemical structure and properties of Azacitidine Impurity 1, often referred to by its systematic name 4-amino-1-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one, are well-documented. This detailed information allows manufacturers and analytical chemists to precisely characterize the material. For pharmaceutical companies, this impurity serves as a benchmark for developing and validating analytical methods. These methods, such as HPLC or Mass Spectrometry, are designed to detect and measure the presence of Azacitidine Impurity 1 in manufactured batches of Azacitidine. The accuracy of these analytical techniques directly relies on the quality and purity of the reference standard used.

When seeking to purchase Azacitidine Impurity 1, it is imperative to partner with reliable manufacturers and suppliers. These entities ensure that the product meets rigorous purity specifications and is accompanied by the necessary documentation, including a Certificate of Analysis (CoA). A comprehensive CoA provides critical details about the impurity's identity, purity level, and the analytical methods used for its characterization. For procurement managers and R&D scientists, selecting a supplier with a proven track record in producing high-quality pharmaceutical intermediates is essential. Many global pharmaceutical markets rely on manufacturers from China, who often offer competitive pricing for these specialized chemical compounds.

The availability of Azacitidine Impurity 1 is critical for various applications within pharmaceutical R&D and quality control. It facilitates the development of precise analytical protocols, supports drug stability studies, and ensures compliance with regulatory standards. By providing access to this essential impurity, manufacturers empower the pharmaceutical industry to uphold the highest standards of drug safety and efficacy. Therefore, companies looking to buy this compound should prioritize suppliers who demonstrate transparency and a commitment to quality in their manufacturing processes.

In summary, Azacitidine Impurity 1 (CAS 157771-77-2) is more than just a byproduct; it is a critical analytical tool. Its availability from reputable manufacturers and suppliers in regions like China ensures that the pharmaceutical industry can continue to produce safe and effective medications. Understanding its role and sourcing it from trusted partners is a key step in maintaining stringent pharmaceutical quality.